Western Blot (WB)
(Western blot analysis of C/EBP alpha (pS193) expression in H9C2 (A), Raw264.7 (B) whole cell lysates.)
Rabbit anti-Mouse, Rat C/EBP alpha (pS193) Polyclonal Antibody | anti-CEBPA antibody
Anti-C/EBP alpha (pS193) Phospho Antibody
Western Blot (WB)
(Western blot analysis of C/EBP alpha (pS193) expression in H9C2 (A), Raw264.7 (B) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of C/EBP alpha (pS193) expression in H9C2 (A), Raw264.7 (B) whole cell lysates.)
NCBI and Uniprot Product Information
NCBI Description
This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. The use of alternative in-frame non-AUG (CUG) and AUG start codons results in several protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the CUG and the first AUG start codons. [provided by RefSeq, Sep 2014]
Uniprot Description
C/EBP-alpha: a bZIP transcription factor which can form homodimers or heterodimers with the related proteins CEBP-beta and CEBP-gamma. Binds to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Protein type: DNA-binding; Transcription factor
Cellular Component: transcription factor complex; Rb-E2F complex; nuclear matrix; protein complex; nucleus
Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein domain specific binding; protein binding; protein homodimerization activity; DNA binding; sequence-specific DNA binding; protein heterodimerization activity; histone deacetylase binding; protein complex binding; transcription factor activity; transcription factor binding
Biological Process: transcription from RNA polymerase II promoter; fat cell differentiation; embryonic placenta development; macrophage differentiation; positive regulation of transcription, DNA-dependent; cell maturation; negative regulation of transcription from RNA polymerase II promoter; glucose homeostasis; negative regulation of cell proliferation; regulation of transcription, DNA-dependent; inner ear development; mitochondrion organization and biogenesis; cholesterol metabolic process; granulocyte differentiation; transcription, DNA-dependent; cytokine and chemokine mediated signaling pathway; liver development; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; positive regulation of osteoblast differentiation; white fat cell differentiation; brown fat cell differentiation; positive regulation of fat cell differentiation; positive regulation of transcription from RNA polymerase III promoter; positive regulation of transcription from RNA polymerase II promoter; myeloid cell differentiation; negative regulation of transcription, DNA-dependent; lung development; urea cycle
Research Articles on CEBPA
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Product Notes
The CEBPA cebpa (Catalog #AAA820794) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-C/EBP alpha (pS193) Phospho Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's C/EBP alpha (pS193) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB (1/500 - 1/1000). Researchers should empirically determine the suitability of the CEBPA cebpa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C/EBP alpha (pS193), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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