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Western Blot (WB) (Western blot analysis of HBP1 (pS402) expression in HEK293T PMA-treated (A), mouse spleen (B), rat spleen (C) whole cell lysates.)

Rabbit HBP1 (pS402) Polyclonal Antibody | anti-HBP1 antibody

Anti-HBP1 (pS402) Phospho Antibody

Reactivity
Human, Mouse, Rat, Bovine, Monkey
Applications
Western Blot
Purity
The antibody was purified by immunogen affinity chromatography.
Synonyms
HBP1 (pS402); Polyclonal Antibody; Anti-HBP1 (pS402) Phospho Antibody; HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1; anti-HBP1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat, Bovine, Monkey
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of HBP1 (pS402) protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Sequence Length
524
Applicable Applications for anti-HBP1 antibody
Western Blot (WB)
Application Notes
WB (1/500 - 1/1000)
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human HBP1. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of HBP1 (pS402) expression in HEK293T PMA-treated (A), mouse spleen (B), rat spleen (C) whole cell lysates.)

Western Blot (WB) (Western blot analysis of HBP1 (pS402) expression in HEK293T PMA-treated (A), mouse spleen (B), rat spleen (C) whole cell lysates.)
Related Product Information for anti-HBP1 antibody
Rabbit polyclonal antibody to HBP1 (pS402)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
57,699 Da
NCBI Official Full Name
HMG box-containing protein 1 isoform 1
NCBI Official Synonym Full Names
HMG-box transcription factor 1
NCBI Official Symbol
HBP1
NCBI Protein Information
HMG box-containing protein 1; HMG box transcription factor 1; high mobility group box transcription factor 1
UniProt Protein Name
HMG box-containing protein 1
UniProt Gene Name
HBP1
UniProt Entry Name
HBP1_HUMAN

Uniprot Description

HBP1: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 7q22.3

Cellular Component: nucleoplasm

Molecular Function: protein binding; DNA binding; RNA binding

Biological Process: Wnt receptor signaling pathway; regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of potassium ion transport; cell cycle arrest

Research Articles on HBP1

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Product Notes

The HBP1 hbp1 (Catalog #AAA820367) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-HBP1 (pS402) Phospho Antibody reacts with Human, Mouse, Rat, Bovine, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's HBP1 (pS402) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB (1/500 - 1/1000). Researchers should empirically determine the suitability of the HBP1 hbp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HBP1 (pS402), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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