Immunohistochemistry (IHC)
(Immunochemical staining of human OXR1 in human corpus uteri with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human OXR1 Polyclonal Antibody | anti-OXR1 antibody
Anti-OXR1 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
OXR1; Polyclonal Antibody; Anti-OXR1 Antibody; Rabbit Polyclonal; OXR1 Antibody; Rabbit PAb; Antigen Affinity Purified; oxidation resistance 1; Anti-Nbla00307 Antibody; Anti-TLDC3 Antibody; anti-OXR1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human OXR1
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-OXR1 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:50-1:200
Immunogen
E Coli-derived Human OXR1 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human OXR1 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human OXR1 in human corpus uteri with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human OXR1 in human corpus uteri with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-OXR1 antibody
Oxidation resistance 1 (OXR1) plays an antioxidant role in eukaryotic organisms, including insects. OXR1 contains three conserved domains: LysM, GRAM, and TLDc. The gene encodes at least six transcripts, including some that only consist of the C-terminal TLDc domain. The human OXR1 gene belongs to a class of genes with conserved functions that protect cells from reactive oxygen species (ROS). Oxidation resistance 1 (OXR1) and its downstream target genes have a pivotal role in defense against oxidative stress. The gene was found using a screen of a human cDNA library by its ability to suppress the spontaneous mutator phenotype of an E Coli mutH nth strain. OXR1 participates in protecting larval silkworms from oxidative stress and bacterial infection through the Jun kinase (JNK) pathway.
References
Wang J, et al. (2019) Loss of oxidation resistance 1, oxr1, is associated with an autosomal-recessive neurological disease with cerebellar atrophy and lysosomal dysfunction. Am J Hum Genet 105 (6): 1237-1253.Su LD, et al. (2017) Oxidation resistance 1 (oxr1) participates in silkworm defense against bacterial infection through the jnk pathway. Insect Sci 24 (1): 17-26.Murphy KC, et al. (2012) Structural/functional analysis of the human oxr1 protein: Identification of exon 8 as the anti-oxidant encoding function. BMC Mol Biol 13 26.
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Product Notes
The OXR1 (Catalog #AAA8108601) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-OXR1 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's OXR1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the OXR1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OXR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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