Mouse anti-Human, Mouse Follistatin Monoclonal Antibody | anti-FST antibody
Follistatin Mouse Monoclonal
Protein A+G purification
Protein A+G purification
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human ovary tumor tissue slide using MBS769415 (Follistatin antibody) at dilution of 1:400)
NCBI and Uniprot Product Information
Uniprot Description
FST: Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 5q11.2
Cellular Component: extracellular region
Molecular Function: activin binding; heparan sulfate proteoglycan binding; protein binding; signal transducer activity
Biological Process: hemopoietic progenitor cell differentiation; negative regulation of activin receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; positive regulation of hair follicle development; signal transduction
Disease: Polycystic Ovary Syndrome 1