Rabbit anti-Human BMP3 Polyclonal Antibody | anti-BMP3 antibody

BMP3 Rabbit Polyclonal

Cat. Num. AAA767150

• Gene Names: BMP3; BMP-3A
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: BMP3; Polyclonal Antibody; BMP3 Rabbit Polyclonal; anti-BMP3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 472

• Applicable Applications for anti-BMP3 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: Bone morphogenetic protein 3
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded rat heart using MBS767150 (BMP3 Antibody) at dilution of 1:50)

Western Blot (WB)

(Recombinant protein were subjected to SDS PAGE followed by western blot with MBS767150 (BMP3 Antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 126507087
• NCBI GeneID: 651
• NCBI Accession #: NP_001192.2
• NCBI GenBank Nucleotide #: NM_001201.2
• Molecular Weight: 53,372 Da
• NCBI Official Full Name: bone morphogenetic protein 3 preproprotein
• NCBI Official Synonym Full Names: bone morphogenetic protein 3
• NCBI Official Symbol: BMP3
• NCBI Official Synonym Symbols: BMP-3A
• NCBI Protein Information: bone morphogenetic protein 3
• UniProt Protein Name: Bone morphogenetic protein 3
• Protein Family: Bone morphogenetic protein
• UniProt Gene Name: BMP3
• UniProt Synonym Gene Names: BMP3A; BMP-3; BMP-3A
• UniProt Entry Name: BMP3_HUMAN

NCBI Description

BMP3 belongs to the transforming growth factor-beta (TGFB) superfamily. Bone morphogenic protein, also known as osteogenin, induces bone formation. [provided by RefSeq, Jul 2008]

Uniprot Description

BMP3: Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. Belongs to the TGF-beta family.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q21

Cellular Component: extracellular space

Molecular Function: cytokine activity; growth factor activity; receptor binding; transforming growth factor beta receptor binding

Biological Process: BMP signaling pathway; cartilage development; cell development; cell-cell signaling; growth; osteoblast differentiation; regulation of apoptosis; regulation of MAPKKK cascade; skeletal development