Human FNIP1 (Folliculin-Interacting Protein 1) ELISA Kit | FNIP1 elisa kit
Human FNIP1 (Folliculin-Interacting Protein 1) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). The encoded protein participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. [provided by RefSeq, Jul 2017]
Uniprot Description
FNIP1: May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1. Belongs to the FNIP family. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 5q23.3
Cellular Component: cytoplasm
Molecular Function: protein binding; guanyl-nucleotide exchange factor activity
Biological Process: regulation of protein amino acid phosphorylation; negative regulation of TOR signaling pathway; TOR signaling pathway; positive regulation of B cell apoptosis; immature B cell differentiation; negative regulation of caspase activity; negative regulation of transcription from RNA polymerase II promoter; positive regulation of protein amino acid phosphorylation; cellular response to starvation; positive regulation of peptidyl-serine phosphorylation; positive regulation of GTPase activity
Research Articles on FNIP1
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Product Notes
The Human FNIP1 fnip1 (Catalog #AAA7608001) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7608001 ELISA Kit recognizes Human FNIP1. It is sometimes possible for the material contained within the vial of "FNIP1 (Folliculin-Interacting Protein 1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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