Human C1orf31 (Cytochrome c oxidase assembly factor 6 homolog) ELISA Kit | C1orf31 elisa kit

Human C1orf31 (Cytochrome c oxidase assembly factor 6 homolog) ELISA Kit

Cat. Num. AAA7606216

• Gene Names: COA6; C1orf31; CEMCOX4
• Reactivity: Human
• Synonyms: C1orf31 (Cytochrome c oxidase assembly factor 6 homolog); Human C1orf31 (Cytochrome c oxidase assembly factor 6 homolog) ELISA Kit; C1orf31 elisa kit

• Reactivity: Human
• Sequence Length: 155

• Samples: Serum, plasma and other biological fluids.
• Assay Type: Sandwich ELISA, Double Antibody
• Detection Range: 0.313-20ng/ml
• Sensitivity: 0.188ng/ml
• Preparation and Storage: Store at 4 degree C if kit is to be used within 1 week. Stable for 6 months (if micro ELISA Plate, Lyophilized Standard and Concentrated Biotinylated Detection Protein stored at-20 degree C. Other components at 2-8 degree C). Stable for 12 months (if the entire kit is stored at-20 degree C).

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for C1orf31 elisa kit

Principle of the Assay: This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti- C1orf31 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti- C1orf31 antibody was used as detection antibodies. The standards, test samples and biotin conjugated detection antibody were added to the wells subsequently, and washed with wash buffer. HRP-Streptavidin was added and unbound conjugates were washed away with wash buffer. TMB substrates were used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the C1orf31 amount of sample captured in plate. Read the O.D. absorbance at 450nm in a microplate reader, and then the concentration of C1orf31 can be calculated.

NCBI and Uniprot Product Information

• NCBI GI #: 683524009
• NCBI GeneID: 388753
• NCBI Accession #: NP_001193570.2
• NCBI GenBank Nucleotide #: NM_001206641.2
• Molecular Weight: 9,428 Da
• NCBI Official Full Name: cytochrome c oxidase assembly factor 6 homolog isoform 2
• NCBI Official Synonym Full Names: cytochrome c oxidase assembly factor 6
• NCBI Official Symbol: COA6
• NCBI Official Synonym Symbols: C1orf31; CEMCOX4
• NCBI Protein Information: cytochrome c oxidase assembly factor 6 homolog
• UniProt Protein Name: Cytochrome c oxidase assembly factor 6 homolog
• UniProt Gene Name: COA6
• UniProt Synonym Gene Names: C1orf31

NCBI Description

This gene encodes a member of the cytochrome c oxidase subunit 6B family. The encoded protein associates with cytochrome c oxidase may act has an cytochrome c oxidase mitochondrial respiratory complex VI assembly factor. Mutations in this gene may be associated with fatal infantile cardiomyopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Uniprot Description

COA6: Belongs to the cytochrome c oxidase subunit 6B family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 1q42.2

Cellular Component: mitochondrial intermembrane space; mitochondrion

Molecular Function: copper ion binding; protein binding; RNA binding

Biological Process: plasma membrane ATP synthesis coupled electron transport; respiratory chain complex IV assembly

Disease: Cardioencephalomyopathy, Fatal Infantile, Due To Cytochrome C Oxidase Deficiency 4