Donkey ATP Binding Cassette Transporter C3 ELISA Kit | ABCC3 elisa kit

Donkey ATP Binding Cassette Transporter C3 ELISA Kit

• Gene Names: ABCC3; MLP2; MRP3; ABC31; MOAT-D; cMOAT2; EST90757
• Reactivity: Donkey
• Synonyms: ATP Binding Cassette Transporter C3; Donkey ATP Binding Cassette Transporter C3 ELISA Kit; ABCC3 elisa kit

• Reactivity: Donkey
• Sequence Length: 573

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 30046456
• NCBI GeneID: 8714
• UniProt Accession #: O15438; O60265; O60922; O75621; O95078; O95289; O95290; Q86X85; Q9UN52; B2RPA9; D3DTX9
• Molecular Weight: 169,343 Da
• NCBI Official Full Name: ABCC3 protein, partial
• NCBI Official Synonym Full Names: ATP-binding cassette, sub-family C (CFTR/MRP), member 3
• NCBI Official Symbol: ABCC3
• NCBI Official Synonym Symbols: MLP2; MRP3; ABC31; MOAT-D; cMOAT2; EST90757
• NCBI Protein Information: canalicular multispecific organic anion transporter 2; multidrug resistance associated protein; multidrug resistance-associated protein 3; ATP-binding cassette sub-family C member 3; multi-specific organic anion transporter D; canicular multispecific organic anion transporter
• UniProt Protein Name: Canalicular multispecific organic anion transporter 2
• Protein Family: ABC transporter C family
• UniProt Gene Name: ABCC3
• UniProt Synonym Gene Names: CMOAT2; MLP2; MRP3; MOAT-D
• UniProt Entry Name: MRP3_HUMAN

NCBI Description

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

Uniprot Description

ABCC3: May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Transporter, ABC family; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q22

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: ATPase activity, coupled to transmembrane movement of substances; organic anion transmembrane transporter activity; ATP binding

Biological Process: bile acid and bile salt transport; transport; bile acid metabolic process; transmembrane transport