Rabbit MRPS21 Polyclonal Antibody | anti-MRPS21 antibody

MRPS21 Rabbit Polyclonal

Cat. Num. AAA7601585

• Gene Names: MRPS21; MDS016; RPMS21; MRP-S21
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: MRPS21; Polyclonal Antibody; MRPS21 Rabbit Polyclonal; anti-MRPS21 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 87

• Applicable Applications for anti-MRPS21 antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Immunogen: Mitochondrial ribosomal protein S21
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney using MBS7601585 (MRPS21 antibody) at dilution of 1:100)

NCBI and Uniprot Product Information

• NCBI GI #: 16306868
• NCBI GeneID: 54460
• Molecular Weight: 10,742 Da
• NCBI Official Full Name: MRPS21 protein
• NCBI Official Synonym Full Names: mitochondrial ribosomal protein S21
• NCBI Official Symbol: MRPS21
• NCBI Official Synonym Symbols: MDS016; RPMS21; MRP-S21
• NCBI Protein Information: 28S ribosomal protein S21, mitochondrial
• UniProt Protein Name: 28S ribosomal protein S21, mitochondrial
• Protein Family: 28S ribosomal protein
• UniProt Gene Name: MRPS21
• UniProt Synonym Gene Names: RPMS21; MRP-S21; S21mt
• UniProt Entry Name: RT21_HUMAN

NCBI Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice variants that differ in the 5' UTR; both transcripts encode the same protein. [provided by RefSeq, Jul 2008]

Uniprot Description

MRPS21: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice variants that differ in the 5' UTR; both transcripts encode the same protein. [provided by RefSeq, Jul 2008]

Protein type: Mitochondrial; Ribosomal

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: mitochondrial inner membrane; mitochondrial small ribosomal subunit

Molecular Function: structural constituent of ribosome

Biological Process: mitochondrial translation; translation