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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human placenta tissue slide using MBS7600229 (PGDS Antibody) at dilution of 1:50)

Rabbit anti-Human, Mouse HPGDS Polyclonal Antibody | anti-HPGDS antibody

HPGDS Rabbit Polyclonal

Gene Names
HPGDS; GSTS; PGD2; PGDS; GSTS1; GSTS1-1
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
HPGDS; Polyclonal Antibody; HPGDS Rabbit Polyclonal; anti-HPGDS antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
199
Applicable Applications for anti-HPGDS antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen
Prostaglandin D2 synthase, hematopoietic
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human placenta tissue slide using MBS7600229 (PGDS Antibody) at dilution of 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human placenta tissue slide using MBS7600229 (PGDS Antibody) at dilution of 1:50)

Western Blot (WB)

(mouse small intestine tissue were subjected to SDS PAGE followed by western blot with MBS7600229 (PGDS antibody) at dilution of 1:1000)

Western Blot (WB) (mouse small intestine tissue were subjected to SDS PAGE followed by western blot with MBS7600229 (PGDS antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23,344 Da
NCBI Official Full Name
hematopoietic prostaglandin D synthase
NCBI Official Synonym Full Names
hematopoietic prostaglandin D synthase
NCBI Official Symbol
HPGDS
NCBI Official Synonym Symbols
GSTS; PGD2; PGDS; GSTS1; GSTS1-1
NCBI Protein Information
hematopoietic prostaglandin D synthase
UniProt Protein Name
Hematopoietic prostaglandin D synthase
UniProt Gene Name
HPGDS
UniProt Synonym Gene Names
GSTS; PGDS; PTGDS2; H-PGDS
UniProt Entry Name
HPGDS_HUMAN

NCBI Description

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. [provided by RefSeq, Jul 2008]

Uniprot Description

Ptgds2: Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide. Belongs to the GST superfamily. Sigma family.

Protein type: Lipid Metabolism - arachidonic acid; Isomerase; EC 2.5.1.18; EC 5.3.99.2

Chromosomal Location of Human Ortholog: 4q22.3

Cellular Component: cytoplasm; cytosol

Molecular Function: calcium ion binding; glutathione transferase activity; magnesium ion binding; prostaglandin-D synthase activity; protein binding; protein homodimerization activity

Biological Process: cyclooxygenase pathway; locomotory behavior; prostaglandin metabolic process; signal transduction

Research Articles on HPGDS

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Product Notes

The HPGDS hpgds (Catalog #AAA7600229) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HPGDS Rabbit Polyclonal reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's HPGDS can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the HPGDS hpgds for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HPGDS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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