Sheep 26S Proteasome Non ATPase Regulatory Subunit 2 (PSMD2) ELISA Kit | PSMD2 elisa kit

Sheep 26S Proteasome Non ATPase Regulatory Subunit 2 (PSMD2) ELISA Kit

Cat. Num. AAA7266449

• Gene Names: PSMD2; S2; P97; RPN1; TRAP2
• Reactivity: Sheep
• Synonyms: 26S Proteasome Non ATPase Regulatory Subunit 2 (PSMD2); Sheep 26S Proteasome Non ATPase Regulatory Subunit 2 (PSMD2) ELISA Kit; PSMD2 elisa kit

• Reactivity: Sheep
• Sequence Length: 778

• Reproducibility: Intra-Assay: CV<10%; Inter-Assay: CV<15%
• Reactivity Note: No significant cross-reactivity or interference between this antigen and analogues was observed. NOTE: Limited by current skills and knowledge, it is impossible for us to complete the cross-reactivity detection, therefore, cross reaction may still exist in some cases.
• Preparation and Storage: Store at 2-8 degree C.; The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.

Related Product Information for PSMD2 elisa kit

This ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of the targets.

Product Categories/Family for PSMD2 elisa kit

Cell Biology

NCBI and Uniprot Product Information

• NCBI GI #: 523425734
• NCBI GeneID: 5708
• NCBI Accession #: NP_001265637.1
• NCBI GenBank Nucleotide #: NM_001278708.1
• UniProt Accession #: Q13200; Q12932; Q15321; Q53XQ4; Q96I12; B4DX07; B4DXY1; E7EW34; E9PCS3
• Molecular Weight: 82,193 Da
• NCBI Official Full Name: 26S proteasome non-ATPase regulatory subunit 2 isoform 2
• NCBI Official Synonym Full Names: proteasome 26S subunit, non-ATPase 2
• NCBI Official Symbol: PSMD2
• NCBI Official Synonym Symbols: S2; P97; RPN1; TRAP2
• NCBI Protein Information: 26S proteasome non-ATPase regulatory subunit 2
• UniProt Protein Name: 26S proteasome non-ATPase regulatory subunit 2
• Protein Family: 26S proteasome non-ATPase regulatory
• UniProt Gene Name: PSMD2
• UniProt Synonym Gene Names: TRAP2

NCBI Description

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

Uniprot Description

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.