Guinea Pig Claudin-10 (CLDN10) ELISA Kit | CLDN10 elisa kit
Guinea pig Claudin-10 (CLDN10) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.[provided by RefSeq, Jun 2010]
Uniprot Description
Claudin-10: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Belongs to the claudin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Cell adhesion
Chromosomal Location of Human Ortholog: 13q31-q34
Cellular Component: tight junction; cytoplasm; plasma membrane; integral to membrane
Molecular Function: identical protein binding; structural molecule activity
Biological Process: ion transport; cell adhesion; calcium-independent cell-cell adhesion
Research Articles on CLDN10
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Product Notes
The Guinea Pig CLDN10 cldn10 (Catalog #AAA7249663) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7249663 ELISA Kit recognizes Guinea Pig CLDN10. It is sometimes possible for the material contained within the vial of "Claudin-10 (CLDN10), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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