Human Acyl coenzyme A thioesterase 11 ELISA Kit | ACOT11 elisa kit
Human Acyl coenzyme A thioesterase 11 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
Uniprot Description
ACOT11: Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Hydrolase; EC 3.1.2.-
Chromosomal Location of Human Ortholog: 1p32.3
Cellular Component: cytoplasm
Molecular Function: acyl-CoA hydrolase activity; lipid binding
Biological Process: response to temperature stimulus; response to cold; fatty acid metabolic process