Bovine cAMP-dependent protein kinase type I-beta regulatory subunit (PRKAR1B) ELISA Kit | PRKAR1B elisa kit

Bovine cAMP-dependent protein kinase type I-beta regulatory subunit (PRKAR1B) ELISA Kit

Cat. Num. AAA7246907

• Gene Names: PRKAR1B; PRKAR1
• Reactivity: Bovine
• Synonyms: cAMP-dependent protein kinase type I-beta regulatory subunit (PRKAR1B); Bovine cAMP-dependent protein kinase type I-beta regulatory subunit (PRKAR1B) ELISA Kit; PRKAR1B elisa kit

• Reactivity: Bovine

• Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
• Preparation and Storage: Store all reagents at 2-8 degree C.

Product Categories/Family for PRKAR1B elisa kit

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 258613977
• NCBI GeneID: 5575
• NCBI Accession #: NP_001158233.1
• NCBI GenBank Nucleotide #: NM_001164761.1
• Molecular Weight: 43,073 Da
• NCBI Official Full Name: cAMP-dependent protein kinase type I-beta regulatory subunit
• NCBI Official Synonym Full Names: protein kinase, cAMP-dependent, regulatory, type I, beta
• NCBI Official Symbol: PRKAR1B
• NCBI Official Synonym Symbols: PRKAR1
• NCBI Protein Information: cAMP-dependent protein kinase type I-beta regulatory subunit
• UniProt Protein Name: cAMP-dependent protein kinase type I-beta regulatory subunit
• Protein Family: cAMP-dependent protein kinase
• UniProt Gene Name: PRKAR1B
• UniProt Entry Name: KAP1_HUMAN

NCBI Description

Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.[supplied by OMIM, Jun 2009]

Uniprot Description

PKAR1B: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. The inactive holoenzyme is composed of two regulatory chains and two catalytic chains. Activation by cAMP releases the two active catalytic monomers and the regulatory dimer. Interacts with PRKX; regulates this cAMP-dependent protein kinase. Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible. Belongs to the cAMP-dependent kinase regulatory chain family.

Protein type: Protein kinase, regulatory subunit

Chromosomal Location of Human Ortholog: 7p22

Cellular Component: plasma membrane; cytosol; cAMP-dependent protein kinase complex

Molecular Function: cAMP-dependent protein kinase inhibitor activity; cAMP-dependent protein kinase regulator activity; cAMP binding

Biological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; water transport; activation of protein kinase A; signal transduction; protein amino acid phosphorylation; learning and/or memory; phospholipase C activation; energy reserve metabolic process; renal water homeostasis; innate immune response; blood coagulation; transmembrane transport; regulation of insulin secretion