Mouse Corticosteroid Binding Globulin (CBG) ELISA Kit | SERPINA6 elisa kit
Mouse Corticosteroid Binding Globulin (CBG) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events. [provided by RefSeq, Jul 2008]
Uniprot Description
SERPINA6: Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. Defects in SERPINA6 are a cause of corticosteroid-binding globulin deficiency (CBG deficiency). CBG deficiency is an extremely rare hereditary disorder characterized by reduced corticosteroid-binding capacity with normal or low plasma corticosteroid-binding globulin concentration, and normal or low basal cortisol levels associated with hypo/hypertension and muscle fatigue. Belongs to the serpin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 14q32.1
Cellular Component: extracellular space
Molecular Function: serine-type endopeptidase inhibitor activity; steroid binding
Biological Process: glucocorticoid metabolic process; transport
Disease: Corticosteroid-binding Globulin Deficiency
Research Articles on SERPINA6
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Product Notes
The Mouse SERPINA6 serpina6 (Catalog #AAA7244722) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7244722 ELISA Kit recognizes Mouse SERPINA6. It is sometimes possible for the material contained within the vial of "Corticosteroid Binding Globulin (CBG), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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