Guinea Pig Connector enhancer of kinase suppressor of ras 2 (CNKSR2) ELISA Kit | CNKSR2 elisa kit
Guinea pig Connector enhancer of kinase suppressor of ras 2 (CNKSR2) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Uniprot Description
CNKSR2: a RAF-binding multidomain protein required for RAS signaling. Contains several protein-protein interaction domains. Its PH domain interacts with Rho in a GTP-dependent manner. Associates with Rhophilin and RalGDS, Rho and Ras effector molecules. Two alternatively spliced isoforms have been described.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: Xp22.12
Cellular Component: Golgi apparatus; postsynaptic membrane; neuron projection; cell soma; plasma membrane
Molecular Function: identical protein binding
Biological Process: regulation of signal transduction
Research Articles on CNKSR2
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Product Notes
The Guinea Pig CNKSR2 cnksr2 (Catalog #AAA7239371) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7239371 ELISA Kit recognizes Guinea Pig CNKSR2. It is sometimes possible for the material contained within the vial of "Connector enhancer of kinase suppressor of ras 2 (CNKSR2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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