Monkey Tubulin-specific chaperone A (TBCA) ELISA Kit | TBCA elisa kit
Monkey Tubulin-specific chaperone A (TBCA) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Uniprot Description
TBCA: Tubulin-folding protein; involved in the early step of the tubulin folding pathway. Belongs to the TBCA family.
Protein type: Chaperone
Chromosomal Location of Human Ortholog: 5q14.1
Cellular Component: microtubule cytoskeleton; microtubule; cytoplasm; nucleolus
Molecular Function: chaperone binding; unfolded protein binding
Biological Process: tubulin folding; 'de novo' posttranslational protein folding; cellular protein metabolic process; protein folding; post-chaperonin tubulin folding pathway