Guinea Pig Arginine-glutamic acid dipeptide repeats protein (RERE) ELISA Kit | RERE elisa kit
Guinea pig Arginine-glutamic acid dipeptide repeats protein (RERE) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
RERE: Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death. A chromosomal aberration involving RERE is found in the neuroblastoma cell line. Translocation t(1;15)(p36.2;q24). 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear receptor co-regulator; Transcription factor
Chromosomal Location of Human Ortholog: 1p36.23
Cellular Component: histone deacetylase complex; nucleus
Molecular Function: protein binding; zinc ion binding; sequence-specific DNA binding; poly-glutamine tract binding; chromatin binding; transcription factor activity
Biological Process: chromatin remodeling; regulation of transcription, DNA-dependent; transcription, DNA-dependent; multicellular organismal development; NLS-bearing substrate import into nucleus
Research Articles on RERE
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Product Notes
The Guinea Pig RERE rere (Catalog #AAA7219896) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7219896 ELISA Kit recognizes Guinea Pig RERE. It is sometimes possible for the material contained within the vial of "Arginine-glutamic acid dipeptide repeats protein (RERE), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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