Mouse ATP-dependent RNA helicase DDX54 (DDX54) ELISA Kit | DDX54 elisa kit
Mouse ATP-dependent RNA helicase DDX54 (DDX54) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
DDX54: Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors. Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.6.4.13; RNA processing; Nucleolus; Transcription, coactivator/corepressor; Helicase; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 12q24.13
Cellular Component: membrane; nucleolus; nucleus
Molecular Function: estrogen receptor binding; transcription corepressor activity; ATP binding; ATP-dependent RNA helicase activity; receptor binding
Biological Process: RNA processing; estrogen receptor signaling pathway; regulation of transcription, DNA-dependent; transcription, DNA-dependent; RNA metabolic process
Research Articles on DDX54
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Product Notes
The Mouse DDX54 ddx54 (Catalog #AAA7205134) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7205134 ELISA Kit recognizes Mouse DDX54. It is sometimes possible for the material contained within the vial of "ATP-dependent RNA helicase DDX54 (DDX54), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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