Guinea Pig ATP-dependent DNA helicase Q1 (RECQL) ELISA Kit | RECQL elisa kit
Guinea pig ATP-dependent DNA helicase Q1 (RECQL) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
RECQL: DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Interacts with EXO1 and MLH1. High expression in heart, lung, skeletal muscle and kidney, low expression in brain. Belongs to the helicase family. RecQ subfamily.
Protein type: Helicase; DNA repair, damage; EC 3.6.4.12
Chromosomal Location of Human Ortholog: 12p12
Cellular Component: nucleoplasm; membrane; nucleus
Molecular Function: ATP-dependent DNA helicase activity; DNA helicase activity; protein binding; DNA binding; ATP-dependent 3'-5' DNA helicase activity; ATP binding
Biological Process: DNA strand renaturation; DNA replication; DNA repair; DNA duplex unwinding; DNA recombination
Research Articles on RECQL
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Product Notes
The Guinea Pig RECQL recql (Catalog #AAA7200812) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7200812 ELISA Kit recognizes Guinea Pig RECQL. It is sometimes possible for the material contained within the vial of "ATP-dependent DNA helicase Q1 (RECQL), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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