GC-rich sequence DNA-binding factor 2 (GCFC2) Recombinant Protein | GCFC2 recombinant protein

Recombinant Human GC-rich sequence DNA-binding factor 2 (GCFC2)

Cat. Num. AAA718398

• Gene Names: GCFC2; GCF; TCF9; DNABF; C2orf3
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: GC-rich sequence DNA-binding factor 2 (GCFC2); Recombinant Human GC-rich sequence DNA-binding factor 2 (GCFC2); GCFC2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-781, Full length protein
• Sequence: MAHRPKRTFRQRAADSSDSDGAEESPAEPGAPRELPVPGSAEEEPPSGGGRAQVAGLPHRVRGPRGRGRVWASSRRATKAAPRADEGSESRTLDVSTDEEDKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPDAAFIQAARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQNLESSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQAMTFMKRRQDELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIESRRTKRRQARVLSGNCNHQEGTSSDDELPSAEMIDFQKSQGDILQKQKKVFEEVQDDFCNIQNILLKFQQWREKFPDSYYEAFISLCIPKLLNPLIRVQLIDWNPLKLESTGLKEMPWFKSVEEFMDSSVEDSKKESSSDKKVLSAIINKTIIPRLTDFVEFLWDPLSTSQTTSLITHCRVILEEHSTCENEVSKSRQDLLKSIVSRMKKAVEDDVFIPLYPKSAVENKTSPHSKFQERQFWSGLKLFRNILLWNGLLTDDTLQELGLGKLLNRYLIIALLNATPGPDVVKKCNQVAACLPEKWFENSAMRTSIPQLENFIQFLLQSAHKLSRSEFRDEVEEIILILVKIKALNQAESFIGEHHLDHLKSLIKED
• Sequence Length: 781

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for GCFC2 recombinant protein

The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene.

NCBI and Uniprot Product Information

• NCBI GI #: 318083361
• NCBI GeneID: 6936
• NCBI Accession #: NP_001188263.1
• NCBI GenBank Nucleotide #: NM_001201334.1
• UniProt Accession #: P16383; O95032; Q53TY0; Q6P2F2; A4UHQ8; A4UHQ9
• Molecular Weight: 28,048 Da
• NCBI Official Full Name: GC-rich sequence DNA-binding factor 2 isoform 2
• NCBI Official Synonym Full Names: GC-rich sequence DNA-binding factor 2
• NCBI Official Symbol: GCFC2
• NCBI Official Synonym Symbols: GCF; TCF9; DNABF; C2orf3
• NCBI Protein Information: GC-rich sequence DNA-binding factor 2
• UniProt Protein Name: GC-rich sequence DNA-binding factor 2
• Protein Family: GC-rich sequence DNA-binding factor
• UniProt Gene Name: GCFC2
• UniProt Synonym Gene Names: C2orf3; GCF; TCF9; TCF-9

NCBI Description

The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters. Involved in pre-mRNA splicing through regulating spliceosome C complex formation. May play a role during late-stage splicing events and turnover of excised inrons.