Tetratricopeptide repeat protein 1 Recombinant Protein | TPR1 recombinant protein

Recombinant Human Tetratricopeptide repeat protein 1

Cat. Num. AAA717280

• Gene Names: TTC1; TPR1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Tetratricopeptide repeat protein 1; Recombinant Human Tetratricopeptide repeat protein 1; TPR1 recombinant protein

• Host: E Coli
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Liquid containing glycerol
• Sequence Positions: 3-292aa; Partial
• Sequence: EKSENCGVPEDLLNGLKVTDTQEAECAGPPVPDPKNQHSQSKLLRDDEAHLQEDQGEEECFHDCSASFEEEPGADKVENKSNEDVNSSELDEEYLIELEKNMSDEEKQKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQIEERNERLKEEMLGKLKDLGNLVLRPFGLSTENFQIKQDSSTGSYSINFVQNPNNNR
• Sequence Length: 292

• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

Product Categories/Family for TPR1 recombinant protein

Signal Transduction

References

Identification and characterization of two novel tetratricopeptide repeat-containing genes.Murthy A.E., Bernards A., Church D., Wasmuth J., Gusella J.F.DNA Cell Biol. 15:727-735(1996) Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.Nat. Genet. 36:40-45(2004)

NCBI and Uniprot Product Information

• NCBI GI #: 543173164
• NCBI GeneID: 7265
• NCBI Accession #: NP_001269429.1
• NCBI GenBank Nucleotide #: NM_001282500.1
• UniProt Accession #: Q99614; Q9BVT3; B2RCT2; D3DQJ8
• Molecular Weight: 60.3 kDa
• NCBI Official Full Name: tetratricopeptide repeat protein 1
• NCBI Official Synonym Full Names: tetratricopeptide repeat domain 1
• NCBI Official Symbol: TTC1
• NCBI Official Synonym Symbols: TPR1
• NCBI Protein Information: tetratricopeptide repeat protein 1
• UniProt Protein Name: Tetratricopeptide repeat protein 1
• Protein Family: Topless-related protein
• UniProt Gene Name: TTC1
• UniProt Synonym Gene Names: TPR1; TPR repeat protein 1
• UniProt Entry Name: TTC1_HUMAN

NCBI Description

This gene encodes a protein that belongs to the tetratrico peptide repeat superfamily of proteins. The encoded protein plays a role in protein-protein interactions, and binds to the Galpha subunit of G protein-coupled receptors to activate the Ras signaling pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Uniprot Description

TTC1: Interacts with the GAP domain of NF1.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 5q33.3

Cellular Component: cytoplasm; peroxisomal membrane

Molecular Function: protein binding; unfolded protein binding

Biological Process: protein folding