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Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human brain tissue using NPAS4 antibody. )

Rabbit anti-Human, Mouse NPAS4 Polyclonal Antibody | anti-NPAS4 antibody

NPAS4 Antibody

Gene Names
NPAS4; NXF; Le-PAS; PASD10; bHLHe79
Reactivity
Human, Mouse
Applications
ELISA, Immunohistochemistry
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
NPAS4; Polyclonal Antibody; NPAS4 Antibody; Neuronal PAS domain-containing protein 4; Neuronal PAS4; HLH-PAS Transcription factor NXF; anti-NPAS4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid; Rabbit IgG In Phosphate Buffered Saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
Applicable Applications for anti-NPAS4 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:100
Immunogen
Synthesized peptide derived from internal of human NPAS4.
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human brain tissue using NPAS4 antibody. )

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human brain tissue using NPAS4 antibody. )
Product Categories/Family for anti-NPAS4 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
87,117 Da
NCBI Official Full Name
neuronal PAS domain-containing protein 4
NCBI Official Synonym Full Names
neuronal PAS domain protein 4
NCBI Official Symbol
NPAS4
NCBI Official Synonym Symbols
NXF; Le-PAS; PASD10; bHLHe79
NCBI Protein Information
neuronal PAS domain-containing protein 4; neuronal PAS4; HLH-PAS transcription factor NXF; PAS domain-containing protein 10; class E basic helix-loop-helix protein 79
UniProt Protein Name
Neuronal PAS domain-containing protein 4
UniProt Gene Name
NPAS4
UniProt Synonym Gene Names
BHLHE79; NXF; PASD10; Neuronal PAS4; bHLHe79
UniProt Entry Name
NPAS4_HUMAN

NCBI Description

NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008]

Uniprot Description

NPAS4: Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: transcription factor complex; nucleus

Molecular Function: signal transducer activity; protein heterodimerization activity

Biological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; signal transduction

Research Articles on NPAS4

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Product Notes

The NPAS4 npas4 (Catalog #AAA7131483) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NPAS4 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NPAS4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:50-1:100. Researchers should empirically determine the suitability of the NPAS4 npas4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NPAS4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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