Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Rabbit structural maintenance of chromosomes 6 Polyclonal Antibody | anti-SMC6 antibody

Rabbit anti-human structural maintenance of chromosomes 6 polyclonal Antibody

Gene Names
SMC6; SMC-6; hSMC6; SMC6L1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Antigen Affinity Purified
Synonyms
structural maintenance of chromosomes 6; Polyclonal Antibody; Rabbit anti-human structural maintenance of chromosomes 6 polyclonal Antibody; SMC6; FLJ22116; FLJ35534; SMC6L1; anti-SMC6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
1091
Applicable Applications for anti-SMC6 antibody
ELISA (EIA), Western Blot (WB)
Immunogen
Human SMC6
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-47633

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
129,154 Da
NCBI Official Full Name
structural maintenance of chromosomes protein 6
NCBI Official Synonym Full Names
structural maintenance of chromosomes 6
NCBI Official Symbol
SMC6
NCBI Official Synonym Symbols
SMC-6; hSMC6; SMC6L1
NCBI Protein Information
structural maintenance of chromosomes protein 6; SMC protein 6; SMC6 structural maintenance of chromosomes 6-like 1
UniProt Protein Name
Structural maintenance of chromosomes protein 6
UniProt Gene Name
SMC6
UniProt Synonym Gene Names
SMC6L1; SMC protein 6; SMC-6; hSMC6
UniProt Entry Name
SMC6_HUMAN

Uniprot Description

SMC6L1: Core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Required for recruitment of telomeres to PML nuclear bodies. Belongs to the SMC family. SMC6 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA repair, damage

Chromosomal Location of Human Ortholog: 2p24.2

Cellular Component: nucleoplasm; chromosome, telomeric region; PML body; nucleolus; intracellular; nucleus

Molecular Function: protein binding; ATP binding

Biological Process: telomere maintenance via recombination; double-strand break repair via homologous recombination

Research Articles on SMC6

Similar Products

Product Notes

The SMC6 smc6 (Catalog #AAA712018) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human structural maintenance of chromosomes 6 polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's structural maintenance of chromosomes 6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the SMC6 smc6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "structural maintenance of chromosomes 6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.