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Western Blot (WB) (Western Blot analysis of MCF-7 cells using Cerberus Polyclonal Antibody.)

Rabbit anti-Human, Rat CER1 Polyclonal Antibody | anti-CER1 antibody

CER1 Antibody

Gene Names
CER1; DAND4
Reactivity
Human, Rat
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
CER1; Polyclonal Antibody; CER1 Antibody; DAND4; Cerberus; Cerberus-related protein; DAN domain family member 4; anti-CER1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid; In Phosphate Buffered Saline, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Applicable Applications for anti-CER1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
ELISA: 1:20000
Immunogen
Synthesized peptide derived from the Internal region of human Cerberus.
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western Blot analysis of MCF-7 cells using Cerberus Polyclonal Antibody.)

Western Blot (WB) (Western Blot analysis of MCF-7 cells using Cerberus Polyclonal Antibody.)
Product Categories/Family for anti-CER1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
543
NCBI Official Full Name
Cerberus
NCBI Official Synonym Full Names
cerberus 1, DAN family BMP antagonist
NCBI Official Symbol
CER1
NCBI Official Synonym Symbols
DAND4
NCBI Protein Information
cerberus; cerberus-related 1; cerberus-related protein; DAN domain family member 4; cerberus 1, cysteine knot superfamily, homolog
UniProt Protein Name
Cerberus
Protein Family
UniProt Gene Name
CER1
UniProt Synonym Gene Names
DAND4
UniProt Entry Name
CER1_HUMAN

NCBI Description

This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008]

Uniprot Description

CER1: Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak. Belongs to the DAN family.

Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 9p23-p22

Cellular Component: extracellular space; extracellular region

Molecular Function: morphogen activity; protein homodimerization activity; cytokine activity

Biological Process: BMP signaling pathway; anterior/posterior pattern formation; negative regulation of cell proliferation; nervous system development; negative regulation of activin receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; ureteric bud development; gastrulation; determination of dorsal identity; bone mineralization; cell migration involved in gastrulation; negative regulation of BMP signaling pathway; anterior/posterior axis specification

Research Articles on CER1

Similar Products

Product Notes

The CER1 cer1 (Catalog #AAA7117626) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CER1 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CER1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000 ELISA: 1:20000. Researchers should empirically determine the suitability of the CER1 cer1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CER1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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