Rabbit anti-Human SOS1 Polyclonal Antibody | anti-SOS1 antibody

SOS1 Antibody, FITC conjugated

Cat. Num. AAA7109238

• Gene Names: SOS1; GF1; HGF; NS4; GGF1; GINGF; SOS-1
• Reactivity: Human
• Applications: ELISA
• Purity: >95%, Protein G purified
• Synonyms: SOS1; Polyclonal Antibody; SOS1 Antibody; FITC conjugated; Son of sevenless homolog 1; SOS-1; anti-SOS1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 1333

• Applicable Applications for anti-SOS1 antibody: ELISA (EIA)
• Immunogen: Recombinant Human Son of sevenless homolog 1 protein (1140-1281AA)
• Conjugation: FITC
• Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Related Product Information for anti-SOS1 antibody

Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity).

Product Categories/Family for anti-SOS1 antibody

Cancer; Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 15529996
• NCBI GeneID: 6654
• NCBI Accession #: NP_005624.2
• NCBI GenBank Nucleotide #: NM_005633.3
• UniProt Accession #: Q07889; A8K2G3; B4DXG2
• Molecular Weight: 36,073 Da
• NCBI Official Full Name: son of sevenless homolog 1
• NCBI Official Synonym Full Names: SOS Ras/Rac guanine nucleotide exchange factor 1
• NCBI Official Symbol: SOS1
• NCBI Official Synonym Symbols: GF1; HGF; NS4; GGF1; GINGF; SOS-1
• NCBI Protein Information: son of sevenless homolog 1
• UniProt Protein Name: Son of sevenless homolog 1
• Protein Family: Son of sevenless
• UniProt Gene Name: SOS1
• UniProt Synonym Gene Names: SOS-1

NCBI Description

This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008]

Uniprot Description

Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity ().