Rabbit anti-Human CHN2 Polyclonal Antibody | anti-CHN2 antibody

CHN2 Antibody, FITC conjugated

Cat. Num. AAA7106861

• Gene Names: CHN2; BCH; CHN2-3; ARHGAP3; RHOGAP3
• Reactivity: Human
• Applications: ELISA
• Purity: >95%, Protein G purified
• Synonyms: CHN2; Polyclonal Antibody; CHN2 Antibody; FITC conjugated; Beta-chimaerin; Beta-chimerin; Rho GTPase-activating protein 3; ARHGAP3; BCH; anti-CHN2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 332

• Applicable Applications for anti-CHN2 antibody: ELISA (EIA)
• Immunogen: Recombinant Human Beta-chimaerin protein (1-91AA)
• Conjugation: FITC
• Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Related Product Information for anti-CHN2 antibody

GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and could therefore play a role in the progression from low-grade to high-grade tumors.

Product Categories/Family for anti-CHN2 antibody

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 91106928
• NCBI GeneID: 1124
• NCBI Accession #: NP_001035025.1
• NCBI GenBank Nucleotide #: NM_001039936.2
• UniProt Accession #: P52757; Q2M203; Q75MM2; A4D1A2; B3VCF1; B3VCF2; B3VCF3; B3VCF7; B3VCG1; C9J7B0; E9PGE0; F8QPL9
• Molecular Weight: 62,441 Da
• NCBI Official Full Name: beta-chimaerin isoform 1
• NCBI Official Synonym Full Names: chimerin 2
• NCBI Official Symbol: CHN2
• NCBI Official Synonym Symbols: BCH; CHN2-3; ARHGAP3; RHOGAP3
• NCBI Protein Information: beta-chimaerin
• UniProt Protein Name: Beta-chimaerin
• Protein Family: Beta-chimaerin
• UniProt Gene Name: CHN2
• UniProt Synonym Gene Names: ARHGAP3; BCH

NCBI Description

This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that contains a phorbol-ester/diacylglycerol (DAG)-type zinc finger, a Rho-GAP domain, and an SH2 domain. The encoded protein translocates from the cytosol to the Golgi apparatus membrane upon binding by diacylglycerol (DAG). Activity of this protein is important in cell proliferation and migration, and expression changes in this gene have been detected in cancers. A mutation in this gene has also been associated with schizophrenia in men. Alternative transcript splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, May 2014]

Uniprot Description

GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and could therefore play a role in the progression from low-grade to high-grade tumors.