Fetal and adult testis-expressed transcript protein (FATE1) Recombinant Protein | FATE1 recombinant protein

Recombinant Human Fetal and adult testis-expressed transcript protein (FATE1) , partial

• Gene Names: FATE1; CT43; FATE
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Fetal and adult testis-expressed transcript protein (FATE1); Recombinant Human Fetal and adult testis-expressed transcript protein (FATE1); partial; FATE1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 183

• Species: Homo sapiens (Human)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 14861838
• NCBI GeneID: 89885
• NCBI Accession #: NP_149076.1
• NCBI GenBank Nucleotide #: NM_033085.2
• UniProt Accession #: Q969F0
• Molecular Weight: 20,712 Da
• NCBI Official Full Name: fetal and adult testis-expressed transcript protein
• NCBI Official Synonym Full Names: fetal and adult testis expressed 1
• NCBI Official Symbol: FATE1
• NCBI Official Synonym Symbols: CT43; FATE
• NCBI Protein Information: fetal and adult testis-expressed transcript protein
• UniProt Protein Name: Fetal and adult testis-expressed transcript protein
• Protein Family: Fetal and adult testis-expressed transcript protein
• UniProt Gene Name: FATE1
• UniProt Synonym Gene Names: FATE; CT43

NCBI Description

This gene encodes a cancer-testis antigen that is highly expressed in hepatocellular carcinomas and other tumors and weakly expressed in normal tissues except testis. The protein is strongly expressed in spermatogonia, primary spermatocytes, and Sertoli cells in seminiferous tubules. This protein may have a role in the control of early testicular differentiation and cell proliferation. [provided by RefSeq, Jan 2010]

Uniprot Description

Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca2+ transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis (PubMed:27402544). May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling (PubMed:26567849).