Rat chromosome 10 open reading frame 59 ELISA Kit | C10orf59 elisa kit
Rat Renalase/ Monoamine Oxidase-C, RNLS/ MAO-C ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney (Xu et al., 2005 [PubMed 15841207]).[supplied by OMIM, Mar 2008]
Uniprot Description
Function: Catalyzes the oxidation of the less abundant alpha-NAD(P)H isoform to form beta-NAD(P)+. The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.2 PublicationsManual assertion based on experiment in:Ref.4
Catalytic activity: Alpha-NAD(P)H + O2 = beta-NAD(P)+ + H2O2.1 PublicationManual assertion based on experiment in:Ref.6
Cofactor: FAD.1 PublicationManual assertion based on experiment in:Ref.7
Research Articles on C10orf59
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Product Notes
The Rat C10orf59 rnls (Catalog #AAA707117) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA707117 ELISA Kit recognizes Rat C10orf59. It is sometimes possible for the material contained within the vial of "chromosome 10 open reading frame 59, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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