Rabbit anti-Human, Mouse FUNDC1 Polyclonal Antibody | anti-FUNDC1 antibody

FUNDC1 Antibody

Cat. Num. AAA7052997

• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >95%, Protein G purified
• Synonyms: FUNDC1; Polyclonal Antibody; FUNDC1 Antibody; FUN14 domain-containing protein 1; anti-FUNDC1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 155

• Applicable Applications for anti-FUNDC1 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:5000; IHC: 1:20-1:200
• Immunogen: Recombinant Human FUN14 domain-containing protein 1 protein (1-46AA)
• Conjugation: Non-conjugated
• Preservative: 0.03% Proclin 300
• Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western BlotPositive WB detected in: Mouse heart tissueAll lanes: FUNDC1 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 18 KDaObserved band size: 18 KDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human glioma cancer using MBS7052997 at dilution of 1:100)

Related Product Information for anti-FUNDC1 antibody

Acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control.

NCBI and Uniprot Product Information

• NCBI GI #: 28603830
• NCBI GeneID: 139341
• NCBI Accession #: NP_776155.1
• NCBI GenBank Nucleotide #: NM_173794.3
• UniProt Accession #: Q8IVP5
• Molecular Weight: 17,178 Da
• NCBI Official Full Name: FUN14 domain-containing protein 1
• NCBI Official Synonym Full Names: FUN14 domain containing 1
• NCBI Official Symbol: FUNDC1
• NCBI Protein Information: FUN14 domain-containing protein 1
• UniProt Protein Name: FUN14 domain-containing protein 1
• Protein Family: FUN14 domain-containing protein
• UniProt Gene Name: FUNDC1

NCBI Description

This gene encodes a protein with a FUN14 superfamily domain. The function of the encoded protein is not known. [provided by RefSeq, Sep 2011]

Uniprot Description

FUNDC1: Acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control. Belongs to the FUN14 family.

Protein type: Membrane protein, multi-pass; Mitochondrial

Chromosomal Location of Human Ortholog: Xp11.3

Cellular Component: integral to mitochondrial outer membrane; mitochondrial outer membrane

Molecular Function: protein binding

Biological Process: mitochondrion degradation; response to hypoxia