Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human melanoma cancer using MBS7048887 at dilution of 1:100)
Rabbit anti-Human PLA2G10 Polyclonal Antibody | anti-PLA2G10 antibody
PLA2G10 Antibody
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human melanoma cancer using MBS7048887 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human melanoma cancer using MBS7048887 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver cancer using MBS7048887 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver cancer using MBS7048887 at dilution of 1:100)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the phospholipase A2 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This calcium-dependent enzyme hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids. In one example, this enzyme catalyzes the release of arachidonic acid from cell membrane phospholipids, thus playing a role in the production of various inflammatory lipid mediators, such as prostaglandins. The encoded protein may promote the survival of breast cancer cells through its role in lipid metabolism. [provided by RefSeq, Nov 2015]
Uniprot Description
PLA2G10: PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Has a powerful potency for releasing arachidonic acid from cell membrane phospholipids. Prefers phosphatidylethanolamine and phosphatidylcholine liposomes to those of phosphatidylserine. Belongs to the phospholipase A2 family.
Protein type: Cell development/differentiation; EC 3.1.1.4; Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - arachidonic acid; Lipid Metabolism - ether lipid; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - linoleic acid; Motility/polarity/chemotaxis; Phospholipase; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 16p13.1-p12
Cellular Component: extracellular region
Molecular Function: phospholipase A2 activity; phospholipase activity
Biological Process: axon guidance; cholesterol homeostasis; lysophospholipid transport; negative regulation of transcription factor activity; phosphatidic acid biosynthetic process; positive regulation of cellular protein metabolic process; positive regulation of prostaglandin secretion; regulation of macrophage activation
Research Articles on PLA2G10
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Product Notes
The PLA2G10 pla2g10 (Catalog #AAA7048887) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PLA2G10 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PLA2G10 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:20-1:200. Researchers should empirically determine the suitability of the PLA2G10 pla2g10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLA2G10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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