Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human lung tissue using MBS7046438 at dilution 1:100)
Rabbit anti-Human CIR1 Polyclonal Antibody | anti-CIR1 antibody
CIR1 Antibody
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
CIR1; Polyclonal Antibody; CIR1 Antibody; Corepressor interacting with RBPJ 1; CBF1-interacting corepressor; Recepin; CIR; anti-CIR1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
450
Applicable Applications for anti-CIR1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: IHC: 1:20-1:200
Species
Human
Immunogen
Recombinant human Corepressor interacting with RBPJ 1 protein (N-160AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-130722 / sc-9470
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human lung tissue using MBS7046438 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human lung tissue using MBS7046438 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human endometrial cancer using MBS7046438 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human endometrial cancer using MBS7046438 at dilution 1:100)
Related Product Information for anti-CIR1 antibody
May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity). Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23,274 Da
NCBI Official Full Name
corepressor interacting with RBPJ 1
UniProt Protein Name
Corepressor interacting with RBPJ 1
Protein Family
UniProt Gene Name
CIR1
UniProt Synonym Gene Names
CIR
UniProt Entry Name
CIR1_HUMAN
Uniprot Description
CIR: May modulate splice site selection during alternative splicing of pre-mRNAs. Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 2q31.1
Cellular Component: histone deacetylase complex; nucleus
Molecular Function: protein binding; RNA polymerase II transcription factor activity, enhancer binding; transcription corepressor activity; transcription factor activity
Biological Process: negative regulation of transcription, DNA-dependent
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Product Notes
The CIR1 cir1 (Catalog #AAA7046438) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CIR1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CIR1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC: 1:20-1:200. Researchers should empirically determine the suitability of the CIR1 cir1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CIR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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