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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7045857 at dilution of 1:100)

Rabbit anti-Human PDLIM5 Polyclonal Antibody | anti-PDLIM5 antibody

PDLIM5 Antibody

Gene Names
PDLIM5; L9; ENH; LIM; ENH1
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Immunofluorescence
Purity
>95%, Protein G purified
Synonyms
PDLIM5; Polyclonal Antibody; PDLIM5 Antibody; PDZ and LIM domain protein 5; Enigma homolog; Enigma-like PDZ and LIM domains protein; ENH; L9; anti-PDLIM5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
234
Applicable Applications for anti-PDLIM5 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
Species
Human
Immunogen
Recombinant human PDZ and LIM domain protein 5 protein
Conjugate
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-82013 / sc-82014 / sc-133900
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7045857 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7045857 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human endometrial cancer using MBS7045857 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human endometrial cancer using MBS7045857 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunofluorescent analysis of HeLa cells using MBS7045857 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunohistochemistry (IHC) (Immunofluorescent analysis of HeLa cells using MBS7045857 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-PDLIM5 antibody
May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May restrain postsynaptic growth of excitatory synapses (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
52,645 Da
NCBI Official Full Name
PDZ and LIM domain protein 5 isoform d
NCBI Official Synonym Full Names
PDZ and LIM domain 5
NCBI Official Symbol
PDLIM5
NCBI Official Synonym Symbols
L9; ENH; LIM; ENH1
NCBI Protein Information
PDZ and LIM domain protein 5
UniProt Protein Name
PDZ and LIM domain protein 5
UniProt Gene Name
PDLIM5
UniProt Synonym Gene Names
ENH
UniProt Entry Name
PDLI5_HUMAN

NCBI Description

This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Uniprot Description

LIM: an adaptor protein of the Enigma family. Contains three LIM domains and one PDZ domain. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. Enigma family proteins possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 4q22

Cellular Component: actin cytoskeleton; cytosol; membrane; postsynaptic density

Molecular Function: actin binding; actinin binding; protein binding; protein kinase C binding

Biological Process: regulation of synaptogenesis

Research Articles on PDLIM5

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Product Notes

The PDLIM5 pdlim5 (Catalog #AAA7045857) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDLIM5 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PDLIM5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). Researchers should empirically determine the suitability of the PDLIM5 pdlim5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDLIM5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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