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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7044998 at dilution of 1:100)

Rabbit anti-Human BLOC1S2 Polyclonal Antibody | anti-BLOC1S2 antibody

BLOC1S2 Antibody

Gene Names
BLOC1S2; CEAP; BLOS2; BORCS2; CEAP11
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
BLOC1S2; Polyclonal Antibody; BLOC1S2 Antibody; Biogenesis of lysosome-related organelles complex 1 subunit 2; BLOC-1 subunit 2; Centrosome-associated protein; BLOS2; CEAP; anti-BLOC1S2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
99
Applicable Applications for anti-BLOC1S2 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: IHC: 1:20-1:200
Species
Human
Immunogen
Recombinant human Biogenesis of lysosome-related organelles complex 1 subunit 2 protein (C-99AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161392 / sc-161391
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7044998 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7044998 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human brain tissue using MBS7044998 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human brain tissue using MBS7044998 at dilution of 1:100)
Related Product Information for anti-BLOC1S2 antibody
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. May play a role in cell proliferation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
11,489 Da
NCBI Official Full Name
biogenesis of lysosome-related organelles complex 1 subunit 2 isoform 2
NCBI Official Synonym Full Names
biogenesis of lysosomal organelles complex 1 subunit 2
NCBI Official Symbol
BLOC1S2
NCBI Official Synonym Symbols
CEAP; BLOS2; BORCS2; CEAP11
NCBI Protein Information
biogenesis of lysosome-related organelles complex 1 subunit 2
UniProt Protein Name
Biogenesis of lysosome-related organelles complex 1 subunit 2
UniProt Gene Name
BLOC1S2
UniProt Synonym Gene Names
BLOS2; CEAP; BLOC-1 subunit 2
UniProt Entry Name
BL1S2_HUMAN

NCBI Description

This gene encodes a protein with multiple functions. The encoded protein has been found in association with the centrosome, shown to co-localize with gamma-tubulin, and also found to be one of the proteins in the BLOC-1 complex which functions in the formation of lysosome-related organelles. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

Uniprot Description

BLOC1S2: May play a role in cell proliferation. The BLOC-1 complex is required for normal biogenesis of lysosome-related organelles, such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking. Belongs to the BLOC1S2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Mitochondrial; Cell cycle regulation

Chromosomal Location of Human Ortholog: 10q24.31

Cellular Component: gamma-tubulin complex; mitochondrion

Molecular Function: gamma-tubulin binding; protein binding

Biological Process: anterograde axon cargo transport; anterograde synaptic vesicle transport; induction of apoptosis via death domain receptors; neurite development

Research Articles on BLOC1S2

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Product Notes

The BLOC1S2 bloc1s2 (Catalog #AAA7044998) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BLOC1S2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BLOC1S2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC: 1:20-1:200. Researchers should empirically determine the suitability of the BLOC1S2 bloc1s2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BLOC1S2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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