Glutamate carboxypeptidase 2 Recombinant Protein | Folh1 recombinant protein
Glutamate carboxypeptidase 2
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
NCBI Description
catalyzes the release of glutamate from acidic peptides including the neuropeptide N-acetyl-alpha-L-aspartyl-L-glutamate [RGD, Feb 2006]
Uniprot Description
FOLH1: Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Has a preference for tri- alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N- aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression. Belongs to the peptidase M28 family. M28B subfamily. 8 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.17.21; Membrane protein, integral; Protease
Cellular Component: cell surface; integral to membrane; integral to plasma membrane; plasma membrane
Molecular Function: carboxypeptidase activity; dipeptidase activity; metallocarboxypeptidase activity; peptidase activity
Biological Process: folic acid and derivative metabolic process; positive regulation of apoptosis; proteolysis
Research Articles on Folh1
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Product Notes
The Folh1 folh1 (Catalog #AAA7042760) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-752aa; full length protein. The amino acid sequence is listed below: MWNAQQDSDS AEALGRRQRW FCAGTLVLAF TGTFIIGFLF GWFIKPSNDS TSSVSYPGMK KAFLQELKAE NIKKFLYNFT RTPHLAGTQH NFELAKQIHA QWKEFGLDLV ELSDYDVLLS YPNKTHPNYI SIINEDGNEI FKTSLAELSP PGYENISDVV PPYSAFSPQG TPEGDLVYVN YARTEDFFKL ERVMKINCSG KIVIARYGQV FRGNKVKNAQ LAGAKGIILY SDPADYFVPG VKSYPDGWNL PGGGVQRGNV LNLNGAGDPL TPGYPANEYA YRHEFTEAVG LPSIPVHPIG YDDAQKLLEH MGGSAPPDSS WKGGLKVPYN VGPGFAGNFS KQKVKLHIHS YNKVTRIYNV IGTLKGAVEP DRYVILGGHR DAWVFGGIDP QSGAAVVHEI VRTFGTLKKK GWRPRRTILF ASWDAEEFGL LGSTEWAEEH SRLLQERGVA YINADSSIEG NYTLRVDCTP LMHSLVYNLT KELPSPDEGF EGKSLYDSWK EKSPSTEFIG MPRISKLGSG NDFEVFFQRL GIASGRARYT KNWKNNKVSS YPLYHSVYET YELVEKFYDP TFKYHLTVAQ VRGAMVFELA NSIVLPFDCQ SYAVALKKHA ETIYNISMNH PQEMKAYMIS FDSLFSAVNN FTDVASKFNQ RLQDLDKSNP ILLRILNDQL MYLERAFIDP LGLPGRPFYR HIIYAPSSHN KYAGESFPGI YDALFDINNK VDTSKAWREV KRQISIAAFT VQAAAETLRE VD. It is sometimes possible for the material contained within the vial of "Glutamate carboxypeptidase 2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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