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Glutamate carboxypeptidase 2 Recombinant Protein | Folh1 recombinant protein

Glutamate carboxypeptidase 2

Gene Names
Folh1; Naalad
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Glutamate carboxypeptidase 2; Folh1 recombinant protein
Ordering
For Research Use Only!
Host
Cell Free Expression
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Liquid containing glycerol
Sequence Positions
1-752aa; full length protein
Sequence
MWNAQQDSDSAEALGRRQRWFCAGTLVLAFTGTFIIGFLFGWFIKPSNDSTSSVSYPGMKKAFLQELKAENIKKFLYNFTRTPHLAGTQHNFELAKQIHAQWKEFGLDLVELSDYDVLLSYPNKTHPNYISIINEDGNEIFKTSLAELSPPGYENISDVVPPYSAFSPQGTPEGDLVYVNYARTEDFFKLERVMKINCSGKIVIARYGQVFRGNKVKNAQLAGAKGIILYSDPADYFVPGVKSYPDGWNLPGGGVQRGNVLNLNGAGDPLTPGYPANEYAYRHEFTEAVGLPSIPVHPIGYDDAQKLLEHMGGSAPPDSSWKGGLKVPYNVGPGFAGNFSKQKVKLHIHSYNKVTRIYNVIGTLKGAVEPDRYVILGGHRDAWVFGGIDPQSGAAVVHEIVRTFGTLKKKGWRPRRTILFASWDAEEFGLLGSTEWAEEHSRLLQERGVAYINADSSIEGNYTLRVDCTPLMHSLVYNLTKELPSPDEGFEGKSLYDSWKEKSPSTEFIGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWKNNKVSSYPLYHSVYETYELVEKFYDPTFKYHLTVAQVRGAMVFELANSIVLPFDCQSYAVALKKHAETIYNISMNHPQEMKAYMISFDSLFSAVNNFTDVASKFNQRLQDLDKSNPILLRILNDQLMYLERAFIDPLGLPGRPFYRHIIYAPSSHNKYAGESFPGIYDALFDINNKVDTSKAWREVKRQISIAAFTVQAAAETLREVD
Sequence Length
752
Species
Rattus norvegicus (Rat)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Related Product Information for Folh1 recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
Product Categories/Family for Folh1 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
– Da
NCBI Official Full Name
glutamate carboxypeptidase 2
NCBI Official Synonym Full Names
folate hydrolase 1
NCBI Official Symbol
Folh1
NCBI Official Synonym Symbols
Naalad
NCBI Protein Information
glutamate carboxypeptidase 2
UniProt Protein Name
Glutamate carboxypeptidase 2
UniProt Gene Name
Folh1
UniProt Synonym Gene Names
Naalad1; FGCP; GCPII; mGCP; NAALADase I
UniProt Entry Name
FOLH1_RAT

NCBI Description

catalyzes the release of glutamate from acidic peptides including the neuropeptide N-acetyl-alpha-L-aspartyl-L-glutamate [RGD, Feb 2006]

Uniprot Description

FOLH1: Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Has a preference for tri- alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N- aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression. Belongs to the peptidase M28 family. M28B subfamily. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.17.21; Membrane protein, integral; Protease

Cellular Component: cell surface; integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function: carboxypeptidase activity; dipeptidase activity; metallocarboxypeptidase activity; peptidase activity

Biological Process: folic acid and derivative metabolic process; positive regulation of apoptosis; proteolysis

Research Articles on Folh1

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Product Notes

The Folh1 folh1 (Catalog #AAA7042760) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-752aa; full length protein. The amino acid sequence is listed below: MWNAQQDSDS AEALGRRQRW FCAGTLVLAF TGTFIIGFLF GWFIKPSNDS TSSVSYPGMK KAFLQELKAE NIKKFLYNFT RTPHLAGTQH NFELAKQIHA QWKEFGLDLV ELSDYDVLLS YPNKTHPNYI SIINEDGNEI FKTSLAELSP PGYENISDVV PPYSAFSPQG TPEGDLVYVN YARTEDFFKL ERVMKINCSG KIVIARYGQV FRGNKVKNAQ LAGAKGIILY SDPADYFVPG VKSYPDGWNL PGGGVQRGNV LNLNGAGDPL TPGYPANEYA YRHEFTEAVG LPSIPVHPIG YDDAQKLLEH MGGSAPPDSS WKGGLKVPYN VGPGFAGNFS KQKVKLHIHS YNKVTRIYNV IGTLKGAVEP DRYVILGGHR DAWVFGGIDP QSGAAVVHEI VRTFGTLKKK GWRPRRTILF ASWDAEEFGL LGSTEWAEEH SRLLQERGVA YINADSSIEG NYTLRVDCTP LMHSLVYNLT KELPSPDEGF EGKSLYDSWK EKSPSTEFIG MPRISKLGSG NDFEVFFQRL GIASGRARYT KNWKNNKVSS YPLYHSVYET YELVEKFYDP TFKYHLTVAQ VRGAMVFELA NSIVLPFDCQ SYAVALKKHA ETIYNISMNH PQEMKAYMIS FDSLFSAVNN FTDVASKFNQ RLQDLDKSNP ILLRILNDQL MYLERAFIDP LGLPGRPFYR HIIYAPSSHN KYAGESFPGI YDALFDINNK VDTSKAWREV KRQISIAAFT VQAAAETLRE VD. It is sometimes possible for the material contained within the vial of "Glutamate carboxypeptidase 2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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