RPS10 antibody pair

RPS10 Antibody Pair

Cat. Num. AAA7041797

• Gene Names: RPS10; S10; DBA9
• Reactivity: Human, Guinea Pig, Pig, Dog, Chicken
• Applications: ELISA
• Synonyms: RPS10; Polyclonal Antibody Pair; RPS10 Antibody Pair; 40S ribosomal protein S10; RPS10 antibody pair

• Host: Capture: Rabbit; Detection: Rabbit
• Reactivity: Human, Guinea Pig, Pig, Dog, Chicken
• Clonality: Polyclonal
• Isotype: Capture: IgG; Detection: IgG
• Form/Format: Liquid
• Concentration: The concentrations and volumes of the antibodies may vary and be lot specific. Details will be on the vial labels. (varies by lot)
• Sequence Length: 165

• Applicable Applications for RPS10 antibody pair: Sandwich ELISA (EIA)
• Application Notes: We recommend using the capture antibody at a concentration of 1ug/ml and the detection antibody at a concentration of 0.125ug/ml.
• Immunogen Species: Human
• Conjugation: Capture: Non-conjugated; Detection: Biotin conjugated
• Recommended Standard: HeLa cell; HL-60; (Standards are recommendations only. Compatibility of the standards in the user developed application needs to be established and confirmed by the researcher.
• Storage Buffer: Capture: 50% Glycerol, 0.01M PBS, PH 7.4; Detection: 50% Glycerol, 0.01M PBS, PH 7.4
• Other Note: Immunogen information is company proprietary information. Antibodies are sold as a pair and not available separately.
• Preparation and Storage: Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze/thaw cycles. When stored properly, products should be stable for at least 5 months.

NCBI and Uniprot Product Information

• NCBI GI #: 49256436
• NCBI GeneID: 6204
• Molecular Weight: 18,898 Da
• NCBI Official Full Name: RPS10 protein
• NCBI Official Synonym Full Names: ribosomal protein S10
• NCBI Official Symbol: RPS10
• NCBI Official Synonym Symbols: S10; DBA9
• NCBI Protein Information: 40S ribosomal protein S10
• UniProt Protein Name: 40S ribosomal protein S10
• Protein Family: Ribosomal protein
• UniProt Gene Name: RPS10
• UniProt Entry Name: RS10_HUMAN

NCBI Description

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S10E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternate splicing results in multiple transcript variants that encode the same protein. Naturally occurring read-through transcription occurs between this locus and the neighboring locus NUDT3 (nudix (nucleoside diphosphate linked moiety X)-type motif 3).[provided by RefSeq, Feb 2011]

Uniprot Description

RPS10: a ribosomal protein of the S10E family. Located in the cytoplasm and nucleus. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This protein is a component of the 40S subunit.

Protein type: RNA-binding; Ribosomal; Nucleolus; Translation

Chromosomal Location of Human Ortholog: 6p21.31

Cellular Component: cytosol; focal adhesion; membrane; nucleolus; nucleoplasm; ribosome

Molecular Function: protein binding; structural constituent of ribosome

Biological Process: mRNA catabolic process, nonsense-mediated decay; ribosomal small subunit assembly and maintenance; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translation; translational initiation; viral transcription

Disease: Diamond-blackfan Anemia 9