PSMB7 antibody pair

PSMB7 Antibody Pair

Cat. Num. AAA7041754

• Gene Names: PSMB7; Z
• Reactivity: Mouse, Guinea Pig, Bovine, Horse, Pig, Dog, Goat, Sheep
• Applications: ELISA
• Synonyms: PSMB7; Polyclonal Antibody Pair; PSMB7 Antibody Pair; Proteasome subunit beta type-7; Macropain chain Z Multicatalytic endopeptidase complex chain Z Proteasome subunit Z; PSMB7 antibody pair

• Host: Capture: Rabbit; Detection: Rabbit
• Reactivity: Mouse, Guinea Pig, Bovine, Horse, Pig, Dog, Goat, Sheep
• Clonality: Polyclonal
• Isotype: Capture: IgG; Detection: IgG
• Form/Format: Liquid
• Concentration: The concentrations and volumes of the antibodies may vary and be lot specific. Details will be on the vial labels. (varies by lot)
• Sequence Length: 277

• Applicable Applications for PSMB7 antibody pair: Sandwich ELISA (EIA)
• Application Notes: We recommend using the capture antibody at a concentration of 0.5ug/ml and the detection antibody at a concentration of 0.2ug/ml.
• Immunogen Species: Human
• Conjugation: Capture: Non-conjugated; Detection: Biotin conjugated
• Recommended Standard: HeLa cell; HT-29 cell; (Standards are recommendations only. Compatibility of the standards in the user developed application needs to be established and confirmed by the researcher.
• Storage Buffer: Capture: 50% Glycerol, 0.01M PBS, PH 7.4; Detection: 50% Glycerol, 0.01M PBS, PH 7.4
• Other Note: Immunogen information is company proprietary information. Antibodies are sold as a pair and not available separately.
• Preparation and Storage: Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze/thaw cycles. When stored properly, products should be stable for at least 5 months.

NCBI and Uniprot Product Information

• NCBI GI #: 48145559
• NCBI GeneID: 5695
• UniProt Accession #: Q6IBT1; Q99436
• Molecular Weight: 29,937 Da
• NCBI Official Full Name: PSMB7
• NCBI Official Synonym Full Names: proteasome subunit beta 7
• NCBI Official Symbol: PSMB7
• NCBI Official Synonym Symbols: Z
• NCBI Protein Information: proteasome subunit beta type-7
• UniProt Protein Name: Proteasome subunit beta type
• Protein Family: Proteasome
• UniProt Gene Name: PSMB7
• UniProt Entry Name: Q6IBT1_HUMAN

NCBI Description

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Jul 2012]

Uniprot Description

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.