Structural polyprotein Recombinant Protein | C recombinant protein
Recombinant Rubella virus Structural polyprotein
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
Uniprot Description
Capsid protein interacts with genomic RNA and assembles into icosaedric core particles. The resulting nucleocapsid eventually associates with the cytoplasmic domain of E2 at the cell membrane, leading to budding and formation of mature virions. Phosphorylation negatively regulates RNA-binding activity, possibly delaying virion assembly during the viral replication phase. Capsid protein dimerizes and becomes disulfide-linked in the virion, but this interaction seems not to be important for its biological function. Modulates genomic RNA replication. Modulates subgenomic RNA synthesis by interacting with human C1QBP/SF2P32. Induces both perinuclear clustering of mitochondria and the formation of electron-dense intermitochondrial plaques, both hallmarks of rubella virus infected cells. Induces apoptosis when expressed in transfected cells.E2 envelope glycoprotein is responsible for viral attachment to target host cell, by binding to the cell receptor. Its transport to the plasma membrane depends on interaction with E1 protein.E1 envelope glycoprotein is a class II viral fusion protein. Fusion activity is inactive as long as E1 is bound to E2 in mature virion. After virus attachment to target cell and clathrin-mediated endocytosis, acidification of the endosome would induce dissociation of E1/E2 heterodimer and concomitant trimerization of the E1 subunits. This E1 homotrimer is fusion active, and promotes release of viral nucleocapsid in cytoplasm after endosome and viral membrane fusion (). E1 cytoplasmic tail modulates virus release, and the tyrosines residues are critical for this function.
Similar Products
Product Notes
The Structural polyprotein c (Catalog #AAA7039696) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 583-1063aa; Partial (Spike glycoprotein E1 Chain). This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the Structural polyprotein c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: EEAFTYLCTA PGCATQTPVP VRLAGVRFES KIVDGGCFAP WDLEATGACI CEIPTDVSCE GLGAWVPTAP CARIWNGTQR ACTFWAVNAY SSGGYAQLAS YFNPGGSYYK QYHPTACEVE PAFGHSDAAC WGFPTDTVMS VFALASYVQH PHKTVRVKFH TETRTVWQLS VAGVSCNVTT EHPFCNTPHG QLEVQVPPDP GDLVEYIMNY TGNQQSRWGL GSPNCHGPDW ASPVCQRHSP DCSRLVGATP ERPRLRLVDA DDPLLRTAPG PGEVWVTPVI GSQARKCGLH IRAGPYGHAT VEMPEWIHAH TTSDPWHPPG PLGLKFKTVR PVALPRALAP PRNVRVTGCY QCGTPALVEG LAPGGGNCHL TVNGEDVGAF PPGKFVTAAL LNTPPPYQVS CGGESDRASA RVIDPAAQSF TGVVYGTHTT AVSETRQTWA EWAAAHWWQL TLGAICALLL AGLLACCAKC LYYLRGAIAP R . It is sometimes possible for the material contained within the vial of "Structural polyprotein, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
