Transmembrane protein 43 (Tmem43) Recombinant Protein | Tmem43 recombinant protein
Recombinant Mouse Transmembrane protein 43 (Tmem43)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
Uniprot Description
TMEM43: May have an important role in maintaining nuclear envelope structure by organizing protein complexes at the inner nuclear membrane. Required for retaining emerin at the inner nuclear membrane. Defects in TMEM43 are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5); also known as arrhythmogenic right ventricular cardiomyopathy (ARVC5). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall. Belongs to the TMEM43 family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen; Golgi apparatus; integral to membrane; integral to nuclear inner membrane; membrane; nuclear inner membrane; nucleus
Molecular Function: protein self-association
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Product Notes
The Tmem43 tmem43 (Catalog #AAA7031871) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-400aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the Tmem43 tmem43 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: AANYSSTSSR KEHVKVTSEP QPGFLERLSE TSGGMFVGLM TFLLSFYLIF TNEGRALKTA TSLAEGLSLV VSPDSIHSVA PENEGRLVHI IGALRTSKLL SDPNYGVHLP AVKLRRHVEM YQWVETEESS EYTEDGQVKK ETKYSYNTEW RSEIVNSRNF DREIGHKNPS AMAVESFTAT APFVQIGRFF LSAGLIDKID NFKALSLAKL EDPHVDIIRR GDFFYHSENP KYPEVGDVRV SFSYAGLSSD DPDLGPAHVV TVIARQRGDQ LIPYSTKSGD TLLLLHHGDF SAEEVFRREQ KSNSMKTWGL RAAGWMAMFM GLNLMTRILY TLVDWFPVFR DLVNIGLKAF AFCVATSLTL LTVAAGWLFY RPLWAALIGC LALVPIIIAR TRVPAKKLE. It is sometimes possible for the material contained within the vial of "Transmembrane protein 43 (Tmem43), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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