Sphingomyelin phosphodiesterase 2 (Smpd2) Recombinant Protein | Smpd2 recombinant protein
Recombinant Mouse Sphingomyelin phosphodiesterase 2 (Smpd2)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein with similarity to the human nSMase1 protein. In humans, the nSMase1 protein was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase. [provided by RefSeq, Oct 2009]
Uniprot Description
SMPD2: Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2- lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso- sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF. Belongs to the neutral sphingomyelinase family.
Protein type: EC 3.1.4.12; Membrane protein, integral; Phosphodiesterase; Membrane protein, multi-pass; Lipid Metabolism - sphingolipid
Cellular Component: caveola; integral to membrane; intracellular; membrane
Molecular Function: hydrolase activity; metal ion binding; sphingomyelin phosphodiesterase activity
Biological Process: ceramide biosynthetic process; lipid metabolic process; positive regulation of apoptosis; response to mechanical stimulus; sphingolipid metabolic process
Research Articles on Smpd2
Similar Products
Product Notes
The Smpd2 smpd2 (Catalog #AAA7030182) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-419aa; Full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the Smpd2 smpd2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MKLNFSLRLR VFNLNCWDIP YLSKHRADRM KRLGDFLNLE NFDLALLEEV WSEQDFQYLR QRLSLTYPDA HYFRSGMIGS GLCVFSKHPI QEIFQHVYSL NGYPYMFHHG DWFCGKSVGL LVLRLSGLVL NAYVTHLHAE YSRQKDIYFA HRVAQAWELA QFIHHTSKNA DVVLLCGDLN MHPKDLGCCL LKEWTGLHDA FVETEDFKGS DDGCTMVPKN CYVSQQDLGP FPSGIRIDYV LYKAVSEFHV CCETLKTTTG CDPHSDKPFS DHEALMATLY VKHSPPQEDP CTACGPLERS DLISVLREAR TELGLGIAKA RWWAAFSGYV IVWGLSLLVL LCVLAAGEEA REVAIILCIP SVGLVLVAGA VYLFHKQEAK GLCRAQAEML HVLTRETETQ DRGSEPHLAY CLQQEGDRA. It is sometimes possible for the material contained within the vial of "Sphingomyelin phosphodiesterase 2 (Smpd2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
