Chloride intracellular channel protein 4 (Clic4) Recombinant Protein | Clic4 recombinant protein
Recombinant Mouse Chloride intracellular channel protein 4 (Clic4)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
Uniprot Description
CLIC4: Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell- surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical- basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis). Belongs to the chloride channel CLIC family.
Protein type: Membrane protein, integral
Cellular Component: apical part of cell; cell surface; centrosome; cytoplasm; cytoplasmic vesicle; cytosol; integral to membrane; intercellular junction; intracellular; membrane; microtubule cytoskeleton; microvillus; midbody; mitochondrion; nuclear matrix; nucleus; perinuclear region of cytoplasm; plasma membrane
Molecular Function: chloride channel activity; protein binding; protein complex binding; voltage-gated ion channel activity
Biological Process: angiogenesis; apoptosis; branching morphogenesis of a tube; chloride transport; endothelial cell morphogenesis; fertilization; ion transport; keratinocyte differentiation; multicellular organism growth; negative regulation of cell migration; transport; vacuolar acidification
Research Articles on Clic4
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Product Notes
The Clic4 clic4 (Catalog #AAA7011627) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-253aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the Clic4 clic4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: ALSMPLNGLK EEDKEPLIEL FVKAGSDGES IGNCPFSQRL FMILWLKGVV FSVTTVDLKR KPADLQNLAP GTHPPFITFN SEVKTDVNKI EEFLEEVLCP PKYLKLSPKH PESNTAGMDI FAKFSAYIKN SRPEANEALE RGLLKTLQKL DEYLNSPLPD EIDENSMEDI KFSTRRFLDG DEMTLADCNL LPKLHIVKVV AKKYRNFDIP KGMTGIWRYL TNAYSRDEFT NTCPSDKEVE IAYSDVAKRL TK. It is sometimes possible for the material contained within the vial of "Chloride intracellular channel protein 4 (Clic4), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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