Calcitonin gene-related peptide type 1 receptor (Calcrl) Recombinant Protein | Calcrl recombinant protein
Recombinant Rat Calcitonin gene-related peptide type 1 receptor (Calcrl)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
NCBI Description
G-protein coupled receptor for either calcitonin gene-related peptide or adrenomedullin that may play a role in vascular tone [RGD, Feb 2006]
Uniprot Description
CALCRL: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family.
Protein type: Membrane protein, integral; Cell cycle regulation; Membrane protein, multi-pass; GPCR, family 2; Receptor, GPCR
Cellular Component: endoplasmic reticulum; endosome; integral to membrane; lysosome; plasma membrane
Molecular Function: adrenomedullin receptor activity; calcitonin gene-related polypeptide receptor activity; calcitonin receptor activity; protein transporter activity
Biological Process: angiogenesis; calcium ion transport; cAMP biosynthetic process; cell surface receptor linked signal transduction; G-protein signaling, adenylate cyclase activating pathway; heart development; negative regulation of inflammatory response; negative regulation of smooth muscle contraction; positive regulation of cAMP biosynthetic process; positive regulation of cell proliferation; positive regulation of smooth muscle cell proliferation; protein transport; receptor internalization
Research Articles on Calcrl
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Product Notes
The Calcrl calcrl (Catalog #AAA7010725) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 24-464aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the Calcrl calcrl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: ESEEGANQTD LGVTRNKIMT AQYECYQKIM QDPIQQGEGL YCNRTWDGWL CWNDVAAGTE SMQYCPDYFQ DFDPSEKVTK ICDQDGNWFR HPDSNRTWTN YTLCNNSTHE KVKTALNLFY LTIIGHGLSI ASLIISLIIF FYFKSLSCQR ITLHKNLFFS FVCNSIVTII HLTAVANNQA LVATNPVSCK VSQFIHLYLM GCNYFWMLCE GIYLHTLIVV AVFAEKQHLM WYYFLGWGFP LLPACIHAIA RSLYYNDNCW ISSDTHLLYI IHGPICAALL VNLFFLLNIV RVLITKLKVT HQAESNLYMK AVRATLILVP LLGIEFVLFP WRPEGKVAEE VYDYVMHILM HYQGLLVSTI FCFFNGEVQA ILRRNWNQYK IQFGNGFSHS DALRSASYTV STISDVQGYS HDCPTEHLNG KSIQDIENVA LKPEKMYDLV M. It is sometimes possible for the material contained within the vial of "Calcitonin gene-related peptide type 1 receptor (Calcrl), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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