Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Rabbit anti-Human EPHA7 Polyclonal Antibody | anti-EPHA7 antibody

EPHA7 Antibody; Biotin conjugated

Reactivity
Human
Applications
ELISA
Purity
>95%,Protein G purified
Synonyms
EPHA7; Polyclonal Antibody; EPHA7 Antibody; Biotin conjugated; Ephrin type-A receptor 7; EPH homology kinase 3; EHK-3; EPH-like kinase 11; EK11; hEK11; EHK3; HEK11; anti-EPHA7 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%,Protein G purified
Form/Format
Liquid
Sequence Length
993
Applicable Applications for anti-EPHA7 antibody
ELISA (EIA)
Immunogen
Recombinant human Ephrin type-A receptor 7 protein
Conjugation
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1015 / sc-25459 / sc-918
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
Related Product Information for anti-EPHA7 antibody
Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50,521 Da
NCBI Official Full Name
ephrin type-A receptor 7 isoform 2
UniProt Protein Name
Ephrin type-A receptor 7
Protein Family
UniProt Gene Name
EPHA7
UniProt Synonym Gene Names
EHK3; HEK11; EHK-3; EK11; hEK11
UniProt Entry Name
EPHA7_HUMAN

Uniprot Description

EphA7: a widely-expressed receptor tyrosine kinase of the Eph family. Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A2, -A3, -A4 and -A5. Contains 1 sterile alpha motif (SAM) and two fibronectin type III domains.

Protein type: Protein kinase, TK; EC 2.7.10.1; Protein kinase, tyrosine (receptor); Membrane protein, integral; Kinase, protein; TK group; Eph family

Chromosomal Location of Human Ortholog: 6q16.1

Cellular Component: cell soma; dendrite; integral to plasma membrane; neuromuscular junction; plasma membrane; postsynaptic membrane

Molecular Function: ATP binding; axon guidance receptor activity; chemorepellent activity; ephrin receptor binding; GPI-linked ephrin receptor activity; protein binding; protein-tyrosine kinase activity

Biological Process: axon guidance; brain development; branching morphogenesis of a nerve; ephrin receptor signaling pathway; negative chemotaxis; negative regulation of collateral sprouting; negative regulation of synaptogenesis; peptidyl-tyrosine phosphorylation; phosphorylation; positive regulation of neuron apoptosis; positive regulation of protein amino acid phosphorylation; regulation of caspase activity; regulation of cell-cell adhesion; regulation of peptidyl-tyrosine phosphorylation; regulation of protein amino acid autophosphorylation; retinal ganglion cell axon guidance

Similar Products

Product Notes

The EPHA7 epha7 (Catalog #AAA7004865) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EPHA7 Antibody; Biotin conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EPHA7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the EPHA7 epha7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EPHA7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.