Rabbit anti-Human Amphiregulin Polyclonal Antibody | anti-AREG antibody
Rabbit Anti-Human Amphiregulin
Western Blot (WB)
(Western analysis of recombinant human Amphiregulin using a rabbit anti-human Amphiregulin polyclonal antibody.)
Immunofluorescence (IF)
(Immunofluorescence staining of human Amphiregulin in a mixture of primary human endothelial cells (HDLEC, HUVEC) and primary normal human dermal firbroblast (NHDF) with a polyclonal rabbit anti-human Amphiregulin antibody. Conjugated secondary antibody: donkey anti-rabbit ALEXA Flour 488 (1:600) [Dianova].)
Immunofluorescence (IF)
(Immunofluorescence staining of human Amphiregulin in primary normal human dermal fibroblasts (NHDF) and primary human dermal lymphatic endothelial cells (HDLEC) with a polyclonal rabbit anti-human Amphiregulin antibody. Conjugated secondary antibody: donkey anti-rabbit ALEXA Flour 488 (1:600) Dianova].)
Immunofluorescence (IF)
(Immunofluorescence staining (cryo-sections) of vasa vasorum of a human lymphatic collector. (fixed 15 min in 4% PFA) with anti-human Amphiregulin (5ug/ml) and counter staining of nuclei with Dapi. [400X] The experiment was performed by the research group of Prof. Dr. J. Wilting and Dr. K. Buttler, University Göttingen, Germany.)
NCBI and Uniprot Product Information
Uniprot Description
AREG: Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts. Belongs to the amphiregulin family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 4q13.3
Cellular Component: cell surface; endoplasmic reticulum membrane; ER-Golgi intermediate compartment membrane; extracellular space
Molecular Function: epidermal growth factor receptor binding; growth factor activity; protein binding
Biological Process: cell proliferation; cell-cell signaling; COPII coating of Golgi vesicle; epidermal growth factor receptor signaling pathway; ER to Golgi vesicle-mediated transport; G-protein coupled receptor protein signaling pathway; positive regulation of cell proliferation; positive regulation of DNA replication
Similar Products
Product Notes
The AREG areg (Catalog #AAA692251) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Anti-Human Amphiregulin reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Amphiregulin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). Researchers should empirically determine the suitability of the AREG areg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Amphiregulin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.