I-309 (CCL1) active protein
Human I-309 (CCL1)
NCBI and Uniprot Product Information
NCBI Description
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Jul 2013]
Uniprot Description
Function: Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8. Ref.7
Subunit structure: Monomer.
Subcellular location: Secreted.
Induction: By phorbol myristate acetate (PMA).
Sequence similarities: Belongs to the intercrine beta (chemokine CC) family.
Research Articles on I-309 (CCL1)
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Product Notes
The I-309 (CCL1) ccl1 (Catalog #AAA692146) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human I-309 (CCL1) reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: SKSMQVPFSR CCFSFAEQEI PLRAILCYRN TSSICSNEGL IFKLKR GKEA CALDTVGWVQ RHRKMLRHCP SKRK. It is sometimes possible for the material contained within the vial of "I-309 (CCL1), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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