MIA-2 (Melanoma inhibitory activity 2) Active Protein | MIA-2 active protein
Human MIA-2 (Melanoma inhibitory activity 2)
Reactivity
Human
Purity
98 % (SDS-PAGE, HPLC)
Synonyms
MIA-2 (Melanoma inhibitory activity 2); Human MIA-2 (Melanoma inhibitory activity 2); Recombinant Human MIA-2; MIA-2 active protein
Host
E Coli
Reactivity
Human
Purity/Purification
98 % (SDS-PAGE, HPLC)
Form/Format
Lyophilized
Sequence
MLESTKLLAD LKKCGDLECE ALINRVSAMR DYRGPDCRYL NFTKGE EISV YVKLAGERED LWAGSKGKEF GYFPRDAVQI EEVFISEEIQ M STKESDFLC L
Sequence Length
654
Endotoxin Level
< 0.1 ng per ug of MIA-2
Biological Activity
Data not available.
Related Product Information for MIA-2 active protein
MIA2 is a secreted cytokine and a member of the MIA/OTOR family. Members of this family which also includes MIA, OTOR, and TANGO share a Src homology-3 (SH3)-like domain. MIA2 is predominantly expressed in hepatocytes. Elevated levels of MIA2 may represent a clinically useful marker for identification of hepatic disease activity and severity. Recombinant human MIA-2 is a 101 amino acid, 11.5 kDa protein comprising the MIA homologous N-terminal region of the full length MIA-2 protein.
Product Categories/Family for MIA-2 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
11.5 kDa
NCBI Official Full Name
melanoma inhibitory activity protein 2
NCBI Official Synonym Full Names
melanoma inhibitory activity 2
NCBI Official Symbol
MIA2
NCBI Protein Information
melanoma inhibitory activity protein 2
UniProt Protein Name
Melanoma inhibitory activity protein 2
UniProt Gene Name
MIA2
UniProt Entry Name
MIA2_HUMAN
Uniprot Description
Function: May play a role in the pathophysiology of liver disease and may serve as a marker of liver damage.
Subcellular location: Secreted
Potential.
Tissue specificity: Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis.
Sequence similarities: Belongs to the MIA/OTOR family.Contains 1 SH3 domain.
Research Articles on MIA-2
Similar Products
Product Notes
The MIA-2 mia2 (Catalog #AAA692088) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human MIA-2 (Melanoma inhibitory activity 2) reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MLESTKLLAD LKKCGDLECE ALINRVSAMR DYRGPDCRYL NFTKGE EISV YVKLAGERED LWAGSKGKEF GYFPRDAVQI EEVFISEEIQ M STKESDFLC L. It is sometimes possible for the material contained within the vial of "MIA-2 (Melanoma inhibitory activity 2), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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