Kex-2 active protein
Yeast Kex-2
Gene Names
KEX2; QDS1; SRB1; VMA45
Reactivity
Yeast
Purity
> 95% by SDS-PAGE & HPLC analyses
Synonyms
Kex-2; Yeast Kex-2; Endoproteinase Lys/Arg-Arg; Protease KEX2; Proteinase YSCF; Kex-2 active protein
Host
Insect Cells
Reactivity
Yeast
Purity/Purification
> 95% by SDS-PAGE & HPLC analyses
Form/Format
Lyophilized
Sequence
LPVPAPPMDS SLLPVKEAED KLSINDPLFE RQWHLVNPSF PGSDIN VLDL WYNNITGAGV VAAIVDDGLD YENEDLKDNF CAEGSWDFND N TNLPKPRLS DDYHGTRCAG EIAAKKGNNF CGVGVGYNAK ISGIRIL SGD ITTEDEAASL IYGLDVNDIY SCSWGPADDG RHLQGPSDLV KK ALVKGVTE GRDSKGAIYV FASGNGGTRG DNCNYDGYTN SIYSITIG AI DHKDLHPPYS EGCSAVMAVT YSSGSGEYIH SSDINGRCSN SHG GTSAAAP LAAGVYTLLL EANPNLTWRD VQYLSILSAV GLEKNADGD W RDSAMGKKYS HRYGFGKIDA HKLIEMSKTW ENVNAQTWFY LPTL YVSQST NSTEETLESV ITISEKSLQD ANFKRIEHVT VTVDIDTEIR GTTTVDLISP AGIISNLGVV RPRDVSSEGF KDWTFMSVAH WGENG VGDWK IKVKTTENGH RIDFHSWRLK LFGESIDSSK TETFVFGNDK EEVEPAATES TVSQYSASST SISISATSTS SISIGVETSA IPQTTT ASTD PDSDPNTP
Sequence Length
814
Biological Activity
Recombinant Kex-2 from High-5 insect cells contains the same specific activity and recognition sequence specificity as yeast derived KEX-2. 1 milligram of recombinant KEX-2 contains activity equivalent to at least 40 units of yeast derived KEX-2. Cleaves at the carboxyl side of K/R-R.
Related Product Information for Kex-2 active protein
Proteases (also called Proteolytic Enzymes, Peptidases, or Proteinases) are enzymes that hydrolyze the amide bonds within proteins or peptides. Most proteases act in a specific manner, hydrolyzing bonds at or adjacent to specific residues or a specific sequence of residues contained within the substrate protein or peptide. Proteases play an important role in most diseases and biological processes including prenatal and postnatal development, reproduction, signal transduction, the immune response, various autoimmune and degenerative diseases, and cancer. They are also an important research tool, frequently used in the analysis and production of proteins. Kex-2 cleaves at the carboxyl end of the recognition sequences Arg-Arg/X and Lys-Arg/X. Recombinant Yeast Kex-2 is a 60.4 kDa protease consisting of 558 amino acid residues.
Product Categories/Family for Kex-2 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
90,003 Da
NCBI Official Full Name
Kex2p
NCBI Official Symbol
KEX2
NCBI Official Synonym Symbols
QDS1; SRB1; VMA45
NCBI Protein Information
Kex2p
UniProt Protein Name
Kexin
UniProt Gene Name
KEX2
UniProt Synonym Gene Names
QDS1
UniProt Entry Name
KEX2_YEAST
Uniprot Description
Function: Processing of precursors of alpha-factors and killer toxin.
Catalytic activity: Cleavage of -Lys-Arg-|-Xaa- and -Arg-Arg-|-Xaa- bonds to process yeast alpha-factor pheromone and killer toxin precursors.
Cofactor: Binds 3 calcium ions per subunit.
Subcellular location: Golgi apparatus › trans-Golgi network membrane; Single-pass type I membrane protein.
Post-translational modification: O-glycosylated.
Sequence similarities: Belongs to the peptidase S8 family. Furin subfamily.
Research Articles on Kex-2
Similar Products
Product Notes
The Kex-2 kex2 (Catalog #AAA691718) is an Active Protein produced from Insect Cells and is intended for research purposes only. The product is available for immediate purchase. The Yeast Kex-2 reacts with Yeast and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: LPVPAPPMDS SLLPVKEAED KLSINDPLFE RQWHLVNPSF PGSDIN VLDL WYNNITGAGV VAAIVDDGLD YENEDLKDNF CAEGSWDFND N TNLPKPRLS DDYHGTRCAG EIAAKKGNNF CGVGVGYNAK ISGIRIL SGD ITTEDEAASL IYGLDVNDIY SCSWGPADDG RHLQGPSDLV KK ALVKGVTE GRDSKGAIYV FASGNGGTRG DNCNYDGYTN SIYSITIG AI DHKDLHPPYS EGCSAVMAVT YSSGSGEYIH SSDINGRCSN SHG GTSAAAP LAAGVYTLLL EANPNLTWRD VQYLSILSAV GLEKNADGD W RDSAMGKKYS HRYGFGKIDA HKLIEMSKTW ENVNAQTWFY LPTL YVSQST NSTEETLESV ITISEKSLQD ANFKRIEHVT VTVDIDTEIR GTTTVDLISP AGIISNLGVV RPRDVSSEGF KDWTFMSVAH WGENG VGDWK IKVKTTENGH RIDFHSWRLK LFGESIDSSK TETFVFGNDK EEVEPAATES TVSQYSASST SISISATSTS SISIGVETSA IPQTTT ASTD PDSDPNTP. It is sometimes possible for the material contained within the vial of "Kex-2, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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