Mouse anti-Chicken MHC Class I Monoclonal Antibody | anti-gamr-UA-c24 antibody
Mouse Anti-Chicken MHC Class I-UNLB
Reactivity
Chicken
Applications
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Synonyms
MHC Class I; Monoclonal Antibody; Mouse Anti-Chicken MHC Class I-UNLB; Mouse Anti-Chicken MHC Class I - Purified; Unlabeled Antibody; Mouse Anti-Chicken MHC Class I; anti-gamr-UA-c24 antibody
Host
Mouse
Reactivity
Chicken
Clonality
Monoclonal
Isotype
Mouse IgG1 kappa
Clone Number
F21-2
Specificity
A monomorphic epitope on avian MHC Class I molecules (Mr ~ 68 kDa)
Like their mammalian counterparts, avian MHC Class I molecules (also known as B-F antigens) consist of a highly polymorphic alpha-chain (Mr ~ 44 kDa) non-covalently bound to the invariant beta 2-microglobulin subunit (Mr ~ 12 kDa). MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells.1-3 MAb F21-2 also reacts with turkey MHC Class I.4
Like their mammalian counterparts, avian MHC Class I molecules (also known as B-F antigens) consist of a highly polymorphic alpha-chain (Mr ~ 44 kDa) non-covalently bound to the invariant beta 2-microglobulin subunit (Mr ~ 12 kDa). MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells.1-3 MAb F21-2 also reacts with turkey MHC Class I.4
Form/Format
Purified (UNLB) Antibody
Sequence Length
236
Applicable Applications for anti-gamr-UA-c24 antibody
Flow Cytometry; Immunohistochemistry; Immunoprecipitation; Western Blot; Immunoaffinity Chromatography
Characterization
To ensure lot-to-lot consistency, each batch of monoclonal antibody is tested by flow cytometry to conform to characteristics of a standard reference reagent. Representative flow data are included with this product insert.
Preparation and Storage
The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C.
The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C.
The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C.
The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze!
Protect conjugated forms from light. Each reagent is stable for the period shown on the bottle label if stored as directed.
The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C.
The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C.
The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze!
Protect conjugated forms from light. Each reagent is stable for the period shown on the bottle label if stored as directed.
References
1. Salomonsen, J., K. Skjodt, M. Krone and M. Simonsen. 1987. Immunogenetics 25:373-382.
2. L.B. Moller, J. Kaufman, S. Verland, J. Salomonsen, D. Avila, J.D. Lambris and K. Skjodt. 1991. Immunogenetics 34:110-120.
3. Dunon, D., J. Salomonsen, K. Skjodt, J. Kaufman, and B.A. Imhof. 1990. Dev. Immunol. 1:127-135.
5. Salomonsen, J. Personal communication.
2. L.B. Moller, J. Kaufman, S. Verland, J. Salomonsen, D. Avila, J.D. Lambris and K. Skjodt. 1991. Immunogenetics 34:110-120.
3. Dunon, D., J. Salomonsen, K. Skjodt, J. Kaufman, and B.A. Imhof. 1990. Dev. Immunol. 1:127-135.
5. Salomonsen, J. Personal communication.
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
26,573 Da
NCBI Official Full Name
MHC class I
UniProt Protein Name
MHC class I
Protein Family
UniProt Gene Name
gamr-UA-c24
UniProt Entry Name
O98279_GADMO
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Product Notes
The MHC Class I gamr-ua-c24 (Catalog #AAA673929) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Chicken MHC Class I-UNLB reacts with Chicken and may cross-react with other species as described in the data sheet. AAA Biotech's MHC Class I can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry; Immunohistochemistry; Immunoprecipitation; Western Blot; Immunoaffinity Chromatography. Researchers should empirically determine the suitability of the MHC Class I gamr-ua-c24 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MHC Class I, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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