Vasopressin Receptor V1a Peptide | Avpr1a peptide
Vasopressin Receptor V1a (AVR-V1a) (Control Peptide)
Purified
Purified
Vasopressin (AVP, Arginine-8-Vasopressin), the antidiuretic hormone is cyclic nonapeptide invovled in the homeostasis of body fluid osmolality, blood volume, vascular tone, and blood pressure. Specific actions of AVP include inhibition of diuresis, contraction of smooth muscle, stimulation of liver glycogenesis, and modulation of ACTH release from pituitary. AVP belongs to the family of vasocative and mitogenic peptide invovled in normal and pathological cell growth and differentiation.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a receptor for arginine vasopressin, a neurohypophyseal hormone involved in diuresis inhibition, smooth muscle contraction, liver glycogenolysis stimulation and regulation of adrenocorticotropic hormone release from the pituitary. This receptor represents one of three G protein-coupled arginine vasopressin receptors which functions through a phosphotidylinositol-calcium second messenger system in vascular and hepatic tissues. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Involved in social memory formation. Ref.11
Subcellular location: Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note: Located in cytoplasmic vesicles dispersed throughout the cell cytoplasm and to the plasma membrane. Ref.8 Ref.10
Tissue specificity: Localized within gonadotropes of the anterior pituitary of the brain. Broadly distributed throughout the cerebral cortex. Ref.7 Ref.10
Post-translational modification: Palmitoylated on three cysteine residues, of which only two are identified. Ref.9
Miscellaneous: Overexpression of AVPR1A in the brain increases the duration of social memory.
Sequence similarities: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
Sequence caution: The sequence CAA77748.1 differs from that shown. Reason: Erroneous initiation.
Research Articles on Avpr1a
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Product Notes
The Avpr1a avpr1a (Catalog #AAA659454) is a Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Vasopressin Receptor V1a can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Western blot: 1-10ug/ml using ECL., Immunohistochemistry: not tested. It is recommended that the antibody be tried at 2-10ug/ml on paraformaldehyde fixed tissue., ELISA: 0.5-1ug/ml using 1ug/ml control peptide per well. Researchers should empirically determine the suitability of the Avpr1a avpr1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Vasopressin Receptor V1a, Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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