Cadherin Peptide | CELSR2 peptide

Cadherin Peptide (avian) [Leu-Arg-Ala-His-Ala-Val-Asp-Val-Asn-Gly-NH2]

Cat. Num. AAA657969

• Gene Names: CELSR2; EGFL2; MEGF3; CDHF10; Flamingo1
• Purity: Highly Purified; ~95%. Purified by HPLC.
• Synonyms: Cadherin Peptide; Cadherin Peptide (avian) [Leu-Arg-Ala-His-Ala-Val-Asp-Val-Asn-Gly-NH2]; CELSR2 peptide

• Host: Synthetic peptide
• Purity/Purification: Highly Purified; ~95%. Purified by HPLC.
• Form/Format: Supplied as a lyophilized powder.

• Sequence (linear): Leu-Arg-Ala-His-Ala-Val-Asp-Val-Asn-Gly-NH2
• Preparation and Storage: Lyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Product Categories/Family for CELSR2 peptide

Molecular Biology; MB-Peptides

NCBI and Uniprot Product Information

• NCBI GI #: 13325064
• NCBI GeneID: 1952
• NCBI Accession #: NP_001399.1
• NCBI GenBank Nucleotide #: NM_001408.2
• UniProt Accession #: Q9HCU4; Q5T2Y7; Q92566
• Molecular Weight: 317,453 Da
• NCBI Official Full Name: cadherin EGF LAG seven-pass G-type receptor 2
• NCBI Official Synonym Full Names: cadherin, EGF LAG seven-pass G-type receptor 2
• NCBI Official Symbol: CELSR2
• NCBI Official Synonym Symbols: EGFL2; MEGF3; CDHF10; Flamingo1
• NCBI Protein Information: cadherin EGF LAG seven-pass G-type receptor 2; EGF-like protein 2; flamingo homolog 3; cadherin family member 10; EGF-like-domain, multiple 2; epidermal growth factor-like 2; multiple EGF-like domains protein 3; epidermal growth factor-like protein 2; multiple epidermal growth factor-like domains 3; multiple epidermal growth factor-like domains protein 3; cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
• UniProt Protein Name: Cadherin EGF LAG seven-pass G-type receptor 2
• Protein Family: Cadherin EGF LAG seven-pass G-type receptor
• UniProt Gene Name: CELSR2
• UniProt Synonym Gene Names: CDHF10; EGFL2; KIAA0279; MEGF3; EGF-like protein 2
• UniProt Entry Name: CELR2_HUMAN

NCBI Description

The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

Function: Receptor that may have an important role in cell/cell signaling during nervous system formation.

Subcellular location: Cell membrane; Multi-pass membrane protein.

Tissue specificity: Highest expression in brain and testis.

Post-translational modification: The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains

By similarity.

Sequence similarities: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.Contains 9 cadherin domains.Contains 7 EGF-like domains.Contains 1 GPS domain.Contains 1 laminin EGF-like domain.Contains 2 laminin G-like domains.